ID   CSP_AQUAE               Reviewed;          70 AA.
AC   O67327;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1998, sequence version 1.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Cold shock-like protein;
GN   Name=csp; Synonyms=cspC; OrderedLocusNames=aq_1302; ORFNames=aq_1303A;
OS   Aquifex aeolicus (strain VF5).
OC   Bacteria; Aquificae; Aquificales; Aquificaceae; Aquifex.
OX   NCBI_TaxID=224324;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VF5;
RX   PubMed=9537320; DOI=10.1038/32831;
RA   Deckert G., Warren P.V., Gaasterland T., Young W.G., Lenox A.L.,
RA   Graham D.E., Overbeek R., Snead M.A., Keller M., Aujay M., Huber R.,
RA   Feldman R.A., Short J.M., Olsen G.J., Swanson R.V.;
RT   "The complete genome of the hyperthermophilic bacterium Aquifex aeolicus.";
RL   Nature 392:353-358(1998).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AE000657; AAC07291.1; -; Genomic_DNA.
DR   PIR; D70412; D70412.
DR   RefSeq; NP_213891.1; NC_000918.1.
DR   RefSeq; WP_010880829.1; NC_000918.1.
DR   AlphaFoldDB; O67327; -.
DR   SMR; O67327; -.
DR   STRING; 224324.aq_1303a; -.
DR   EnsemblBacteria; AAC07291; AAC07291; aq_1303a.
DR   KEGG; aae:aq_1303a; -.
DR   eggNOG; COG1278; Bacteria.
DR   HOGENOM; CLU_117621_0_3_0; -.
DR   InParanoid; O67327; -.
DR   OMA; IWQKERG; -.
DR   OrthoDB; 2034748at2; -.
DR   Proteomes; UP000000798; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0001072; F:transcription antitermination factor activity, RNA binding; IBA:GO_Central.
DR   GO; GO:0060567; P:negative regulation of DNA-templated transcription, termination; IBA:GO_Central.
DR   GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR   CDD; cd04458; CSP_CDS; 1.
DR   Gene3D; 2.40.50.140; -; 1.
DR   InterPro; IPR012156; Cold_shock_CspA.
DR   InterPro; IPR011129; CSD.
DR   InterPro; IPR019844; CSD_1.
DR   InterPro; IPR002059; CSP_DNA-bd.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   Pfam; PF00313; CSD; 1.
DR   PIRSF; PIRSF002599; Cold_shock_A; 1.
DR   PRINTS; PR00050; COLDSHOCK.
DR   SMART; SM00357; CSP; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   PROSITE; PS00352; CSD_1; 1.
DR   PROSITE; PS51857; CSD_2; 1.
PE   3: Inferred from homology;
KW   Activator; Cytoplasm; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..70
FT                   /note="Cold shock-like protein"
FT                   /id="PRO_0000100278"
FT   DOMAIN          5..65
FT                   /note="CSD"
SQ   SEQUENCE   70 AA;  8061 MW;  7F0DA15B0A4B5A9A CRC64;
     MSFRGTVKWF SKDKGYGFIT REDTNADVFV HFTDIQMEGF KTLQKGQKVE FDVVEDTKGP
     RAKNVRVLGE