ID   CSRN1_PONAB             Reviewed;         593 AA.
AC   Q5R638;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Cysteine/serine-rich nuclear protein 1;
DE            Short=CSRNP-1;
DE   AltName: Full=Axin-1 up-regulated gene 1 protein;
GN   Name=CSRNP1; Synonyms=AXUD1;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Binds to the consensus sequence 5'-AGAGTG-3' and has
CC       transcriptional activator activity. May have a tumor-suppressor
CC       function. May play a role in apoptosis (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AXUD1 family. {ECO:0000305}.
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DR   EMBL; CR860658; CAH92778.1; -; mRNA.
DR   RefSeq; NP_001126620.1; NM_001133148.1.
DR   AlphaFoldDB; Q5R638; -.
DR   STRING; 9601.ENSPPYP00000015657; -.
DR   GeneID; 100173617; -.
DR   KEGG; pon:100173617; -.
DR   CTD; 64651; -.
DR   eggNOG; KOG3813; Eukaryota.
DR   InParanoid; Q5R638; -.
DR   OrthoDB; 577123at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   InterPro; IPR031972; CSRNP_N.
DR   InterPro; IPR023260; Cys/Ser-rich_nuc_prot.
DR   PANTHER; PTHR13580; PTHR13580; 1.
DR   Pfam; PF16019; CSRNP_N; 1.
DR   PRINTS; PR02031; CYSSERRICHNP.
PE   2: Evidence at transcript level;
KW   Activator; Apoptosis; DNA-binding; Nucleus; Reference proteome;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..593
FT                   /note="Cysteine/serine-rich nuclear protein 1"
FT                   /id="PRO_0000290119"
FT   REGION          1..66
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          313..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          478..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        15..48
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..372
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   593 AA;  63586 MW;  D8B406D64E4C57A1 CRC64;
     MTGLLKRKFD QLDEDNSSVS SSSSSSSSSS GCQSLSCSPS SSVSRASDSE EEGPWDQMPL
     PDRDFCSPRS FTPLSILKRA RRERPGRVAF DGITVFYFPR CQGFTSVPSR GGCTLGMAPR
     HSACRRFSLA EFAQEQARAR HEKLRQRLKE EKLEMLQWKL SAAGAPKAEA GLPPAVDAID
     DASVEEDLAV AVAGGRLEEV SFLQPYPARR RRALLRASGV RRIDREEKRE LQALRQSRED
     CGCHCDRICD PETCSCSLAG IKCQMDHTAF PCGCCREGCE NPMGRVEFNQ ARVQTHFIHT
     LTRLQLEQEA ESFRELEAPA QGSPPSPGEE ALVPTFPLAK PPMNNELGDN SCSSDMTDSS
     TASSSASGTS GAPDCPTHPG LPGPGFQPGV DDDSLARILS FSDSDFGGEE EEEEEGSVGN
     LDNLSCFHPA DIFGTSDPGG LASWTHSYSG CSFTSGILDE NANLDASCFL NGGLEGSREG
     SLPGTSVPPS MDAGQSSSVD LSLSSCDSFE LLQALPDYSL GPHYTSQKVS DSLDNIEAPH
     FPLPGLSPPG DASSCFLESL MGFSEPAAEA LDPFIDSQFE DTVPASLMEP VPV