CST10_ARATH
ID CST10_ARATH Reviewed; 124 AA.
AC F4IZ80; A0A178VFW8; Q0WPY7; Q9M2X4;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 10 {ECO:0000303|PubMed:29272523};
DE Short=AthCYSTM10 {ECO:0000303|PubMed:29272523};
DE AltName: Full=Protein WINDHOSE 3 {ECO:0000303|PubMed:21658947};
GN Name=CYSTM10 {ECO:0000303|PubMed:29272523};
GN Synonyms=WIH3 {ECO:0000303|PubMed:21658947};
GN OrderedLocusNames=At3g49845 {ECO:0000312|Araport:AT3G49845};
GN ORFNames=T16K5.190 {ECO:0000312|EMBL:CAB66922.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 14-124.
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY.
RX PubMed=21658947; DOI=10.1016/j.cub.2011.05.015;
RA Lieber D., Lora J., Schrempp S., Lenhard M., Laux T.;
RT "Arabidopsis WIH1 and WIH2 genes act in the transition from somatic to
RT reproductive cell fate.";
RL Curr. Biol. 21:1009-1017(2011).
RN [5]
RP FUNCTION, INTERACTION WITH CYSTM7 AND WIH1/CYSTM13, TISSUE SPECIFICITY,
RP INDUCTION BY SALT; HEAT; COLD AND OXIDATION, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=29272523; DOI=10.1093/pcp/pcx202;
RA Xu Y., Yu Z., Zhang D., Huang J., Wu C., Yang G., Yan K., Zhang S.,
RA Zheng C.;
RT "CYSTM, a novel non-secreted cysteine-rich peptide family, involved in
RT environmental stresses in Arabidopsis thaliana.";
RL Plant Cell Physiol. 59:423-438(2018).
CC -!- FUNCTION: Involved in resistance to abiotic stress.
CC {ECO:0000303|PubMed:29272523}.
CC -!- SUBUNIT: Heterodimers (PubMed:29272523). Interacts with CYSTM7 and
CC WIH1/CYSTM13 (PubMed:29272523). {ECO:0000269|PubMed:29272523}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:29272523};
CC Single-pass membrane protein {ECO:0000255}. Cytoplasm
CC {ECO:0000269|PubMed:29272523}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in stems and,at low levels, in
CC stems, roots, flowers, siliques and leaves.
CC {ECO:0000269|PubMed:29272523}.
CC -!- INDUCTION: Induced by heat and oxidation stress in shoots
CC (PubMed:29272523). Induced in roots in response to cold and salt
CC (PubMed:29272523). {ECO:0000269|PubMed:29272523}.
CC -!- SIMILARITY: Belongs to the CYSTM1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB66922.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AL132965; CAB66922.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE78597.1; -; Genomic_DNA.
DR EMBL; AK228923; BAF00812.1; -; mRNA.
DR PIR; T46050; T46050.
DR RefSeq; NP_001118805.1; NM_001125333.2.
DR AlphaFoldDB; F4IZ80; -.
DR STRING; 3702.AT3G49845.1; -.
DR PaxDb; F4IZ80; -.
DR PRIDE; F4IZ80; -.
DR ProteomicsDB; 201786; -.
DR EnsemblPlants; AT3G49845.1; AT3G49845.1; AT3G49845.
DR GeneID; 6240705; -.
DR Gramene; AT3G49845.1; AT3G49845.1; AT3G49845.
DR KEGG; ath:AT3G49845; -.
DR Araport; AT3G49845; -.
DR TAIR; locus:4515103232; AT3G49845.
DR HOGENOM; CLU_128451_1_0_1; -.
DR InParanoid; F4IZ80; -.
DR OMA; PPHYGQA; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; F4IZ80; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:UniProtKB.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR InterPro; IPR044850; WIH2-like.
DR PANTHER; PTHR31568; PTHR31568; 2.
PE 1: Evidence at protein level;
KW Cell membrane; Cytoplasm; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..124
FT /note="Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 10"
FT /id="PRO_0000454807"
FT TRANSMEM 101..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..53
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 65..92
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 124 AA; 13354 MW; 793C51A8C4FCD3B3 CRC64;
MSYQDPQHPV SAPPPQGYPP KEGYPPAGYP PPAGYPPPQY PQAGYPPAGY PPPQQGYGQG
YPAQGYPPPQ YPQGHPPQYP YQGPPPPHYG QAPPKNKKDK KDSGGFMEGC LAMLCCCVLL
EACF
