ID   CST15_BOVIN             Reviewed;         128 AA.
AC   Q2NKZ5;
DT   01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Probable cystatin-15;
DE   Flags: Precursor;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cystatin family. {ECO:0000305}.
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DR   EMBL; BC111315; AAI11316.1; -; mRNA.
DR   RefSeq; NP_001071543.1; NM_001078075.1.
DR   AlphaFoldDB; Q2NKZ5; -.
DR   SMR; Q2NKZ5; -.
DR   PaxDb; Q2NKZ5; -.
DR   Ensembl; ENSBTAT00000039366; ENSBTAP00000039161; ENSBTAG00000027420.
DR   GeneID; 617402; -.
DR   KEGG; bta:617402; -.
DR   VEuPathDB; HostDB:ENSBTAG00000027420; -.
DR   eggNOG; ENOG502TDK9; Eukaryota.
DR   GeneTree; ENSGT00940000165454; -.
DR   HOGENOM; CLU_118168_3_2_1; -.
DR   InParanoid; Q2NKZ5; -.
DR   OMA; YKFLQVR; -.
DR   OrthoDB; 1565344at2759; -.
DR   Proteomes; UP000009136; Chromosome 13.
DR   Bgee; ENSBTAG00000027420; Expressed in spermatocyte and 44 other tissues.
DR   ExpressionAtlas; Q2NKZ5; baseline.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0004869; F:cysteine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR   CDD; cd00042; CY; 1.
DR   InterPro; IPR000010; Cystatin_dom.
DR   InterPro; IPR046350; Cystatin_sf.
DR   Pfam; PF00031; Cystatin; 1.
DR   SMART; SM00043; CY; 1.
DR   SUPFAM; SSF54403; SSF54403; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Protease inhibitor; Reference proteome;
KW   Secreted; Signal; Thiol protease inhibitor.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..128
FT                   /note="Probable cystatin-15"
FT                   /id="PRO_0000285801"
FT   CARBOHYD        104
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   DISULFID        82..92
FT                   /evidence="ECO:0000250"
FT   DISULFID        105..125
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   128 AA;  14955 MW;  BA8E9CD5052431A0 CRC64;
     MFWKLPLLLG LLALGPHVCS WMFEDIGKTG QEFSMCVEFA IHHFNEHQPD ENAYKLLWVR
     RSQHKKFSLT YLMDLHLGRT ICKKHDEDID NCPLQEGPEG KKVNCTFIVD SRPLYTKFTL
     LNSTCQQI