ID   CSTA_HELPJ              Reviewed;         687 AA.
AC   Q9ZK47;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Peptide transporter CstA {ECO:0000305};
DE   AltName: Full=Carbon starvation protein A homolog {ECO:0000305};
GN   Name=cstA; OrderedLocusNames=jhp_1095;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Involved in peptide utilization.
CC       {ECO:0000250|UniProtKB:P15078}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000255}.
CC   -!- SIMILARITY: Belongs to the peptide transporter carbon starvation (CstA)
CC       (TC 2.A.114) family. {ECO:0000305}.
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DR   EMBL; AE001439; AAD06677.1; -; Genomic_DNA.
DR   PIR; C71849; C71849.
DR   RefSeq; WP_001172716.1; NC_000921.1.
DR   AlphaFoldDB; Q9ZK47; -.
DR   STRING; 85963.jhp_1095; -.
DR   EnsemblBacteria; AAD06677; AAD06677; jhp_1095.
DR   KEGG; hpj:jhp_1095; -.
DR   PATRIC; fig|85963.30.peg.1487; -.
DR   eggNOG; COG1966; Bacteria.
DR   OMA; GTISGFH; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0009267; P:cellular response to starvation; IEA:InterPro.
DR   GO; GO:0015833; P:peptide transport; IEA:UniProtKB-KW.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR025299; CstA_C.
DR   InterPro; IPR003706; CstA_N.
DR   Pfam; PF02554; CstA; 1.
DR   Pfam; PF13722; CstA_5TM; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Peptide transport;
KW   Protein transport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..687
FT                   /note="Peptide transporter CstA"
FT                   /id="PRO_0000190048"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..182
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        221..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        325..345
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        373..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        440..460
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        462..482
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        513..533
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        546..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        574..594
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        642..662
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   687 AA;  74152 MW;  A8BAA383EDED8807 CRC64;
     MQKSLVSLAW VFVAILGAIC LGVLALHKGE SINTLWLVVA SACIYSIGYR FYSHFIAYRV
     LKLDDSRATP ACVRNDGKDF VPTDKAITFG HHFAAIAGAG PLVGPILAAQ MGYLPSILWI
     LIGSVLGGCV HDFVVLFASI RRDGKSLGEM IKLEMGKFVG MIASLGILGI MLIIIAILAM
     VVVKALAHSP WGFFTIAMTI PIAILMGLYM RFFRPHKILE VSVIGFILLI IAIYAGKYVS
     LDPKLASIFT FEAGSLAWMI MGYGFVASIL PVWFLLAPRD YLSTFLKIGV IGVLVVAIVF
     VAPPLQIPKI TPFVDGSGPV FAGSVFPFLF ITVACGTISG FHALISSGTT PKMLAKESDA
     RLVGYGSMVM ESVVALMALV CAGILHPGLY FAINSPEVSI GKDIADAASV ISSWGFSISA
     EEIREMTKNI GESSILSRTG GAPTFAIGLA MIVYHILGDP SVMAFWYHFA ILFEALFILT
     AVDAGTRTAR FMIQDLLGNI YKPLGDLSSY KAGIFATLLC VAGWGYFLYQ GTIDPKGGIY
     TLWPLFGVSN QMLAGMALLL VTVVLFKMGR FKGAIISALP AVLILAITFY SGILKVMPKS
     NDSVLNNVSH VAQMQIIKEK IALTTDEKAL KTLQKSFFNH AIDAILCVFF MLVALLVLIV
     SVRICSNAYF KNQIYPPLAE TPYIKAA