CSTM7_ARATH
ID CSTM7_ARATH Reviewed; 97 AA.
AC O22802;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 7 {ECO:0000303|PubMed:29272523};
DE Short=AthCYSTM7 {ECO:0000303|PubMed:29272523};
GN Name=CYSTM7 {ECO:0000303|PubMed:29272523};
GN OrderedLocusNames=At2g33520 {ECO:0000312|Araport:AT2G33520};
GN ORFNames=F4P9.29 {ECO:0000312|EMBL:AAB80669.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP FUNCTION, HOMODIMERIZATION, INTERACTION WITH CYSTM3; CYSTM4; CYSTM5;
RP CYSTM6; CYSTM10; WIH1/CYSTM13; CYSTM11; CYSTM1; CYSTM2 AND CYSTM12, TISSUE
RP SPECIFICITY, INDUCTION BY SALT; HEAT AND DROUGHT, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=29272523; DOI=10.1093/pcp/pcx202;
RA Xu Y., Yu Z., Zhang D., Huang J., Wu C., Yang G., Yan K., Zhang S.,
RA Zheng C.;
RT "CYSTM, a novel non-secreted cysteine-rich peptide family, involved in
RT environmental stresses in Arabidopsis thaliana.";
RL Plant Cell Physiol. 59:423-438(2018).
CC -!- FUNCTION: Involved in resistance to abiotic stress.
CC {ECO:0000303|PubMed:29272523}.
CC -!- SUBUNIT: Homodimer and heterodimers (PubMed:29272523). Interacts with
CC CYSTM3, CYSTM4, CYSTM5, CYSTM6, CYSTM10, WIH1/CYSTM13 and CYSTM11
CC (PubMed:29272523). Binds weakly to CYSTM1, CYSTM2 and CYSTM12
CC (PubMed:29272523). {ECO:0000269|PubMed:29272523}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:29272523};
CC Single-pass membrane protein {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in siliques and, to a lower
CC extent, in stems, roots, leaves and flowers.
CC {ECO:0000269|PubMed:29272523}.
CC -!- INDUCTION: Induced by salt, heat and drought.
CC {ECO:0000269|PubMed:29272523}.
CC -!- SIMILARITY: Belongs to the CYSTM1 family. {ECO:0000305}.
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DR EMBL; AC002332; AAB80669.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08848.1; -; Genomic_DNA.
DR EMBL; BT010807; AAR24174.1; -; mRNA.
DR EMBL; BT011286; AAR92322.1; -; mRNA.
DR PIR; E84746; E84746.
DR RefSeq; NP_180910.1; NM_128912.2.
DR AlphaFoldDB; O22802; -.
DR IntAct; O22802; 1.
DR PaxDb; O22802; -.
DR PRIDE; O22802; -.
DR ProteomicsDB; 193603; -.
DR EnsemblPlants; AT2G33520.1; AT2G33520.1; AT2G33520.
DR GeneID; 817917; -.
DR Gramene; AT2G33520.1; AT2G33520.1; AT2G33520.
DR KEGG; ath:AT2G33520; -.
DR Araport; AT2G33520; -.
DR TAIR; locus:2051124; AT2G33520.
DR HOGENOM; CLU_183260_0_0_1; -.
DR OMA; TRTRYQD; -.
DR OrthoDB; 1602918at2759; -.
DR Proteomes; UP000006548; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR GO; GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.
DR GO; GO:0043621; F:protein self-association; IDA:UniProtKB.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..97
FT /note="Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 7"
FT /id="PRO_0000454804"
FT TRANSMEM 68..88
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 97 AA; 11313 MW; 1D6716FB2337AA43 CRC64;
MASYHVSHDS YQSPGPSPLY QPIIEAPPPP YPPTRTRYQD YYGGYGQPHP PPLRPYRSDH
EYYGDGEYVG CFPFLRSCLT TLCCCWFVEQ CCFRSRY
