CSTM9_ARATH
ID CSTM9_ARATH Reviewed; 72 AA.
AC Q9LHJ3; Q3EB25;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 9 {ECO:0000303|PubMed:29272523};
DE Short=AthCYSTM9 {ECO:0000303|PubMed:29272523};
GN Name=CYSTM9 {ECO:0000303|PubMed:29272523};
GN OrderedLocusNames=At3g22240 {ECO:0000312|Araport:AT3G22240};
GN ORFNames=MMP21.2 {ECO:0000312|EMBL:BAB01942.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, INTERACTION WITH WIH1/CYSTM13, TISSUE SPECIFICITY, INDUCTION BY
RP SALT; HEAT; DROUGHT AND OXIDATION, AND SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=29272523; DOI=10.1093/pcp/pcx202;
RA Xu Y., Yu Z., Zhang D., Huang J., Wu C., Yang G., Yan K., Zhang S.,
RA Zheng C.;
RT "CYSTM, a novel non-secreted cysteine-rich peptide family, involved in
RT environmental stresses in Arabidopsis thaliana.";
RL Plant Cell Physiol. 59:423-438(2018).
CC -!- FUNCTION: Involved in resistance to abiotic stress.
CC {ECO:0000303|PubMed:29272523}.
CC -!- SUBUNIT: Heterodimers (PubMed:29272523). Interacts with WIH1/CYSTM13
CC (PubMed:29272523). {ECO:0000269|PubMed:29272523}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:29272523};
CC Single-pass membrane protein {ECO:0000255}. Nucleus
CC {ECO:0000269|PubMed:29272523}.
CC -!- TISSUE SPECIFICITY: Mostly expressed in roots and flowers and, to a
CC lower extent, in stems, siliques and leaves.
CC {ECO:0000269|PubMed:29272523}.
CC -!- INDUCTION: Induced by heat in shoots (PubMed:29272523). Repressed in
CC roots in response to drought, oxidation stress and salt
CC (PubMed:29272523). {ECO:0000269|PubMed:29272523}.
CC -!- SIMILARITY: Belongs to the CYSTM1 family. {ECO:0000305}.
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DR EMBL; AP002046; BAB01942.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE76611.1; -; Genomic_DNA.
DR EMBL; AK175604; BAD43367.1; -; mRNA.
DR EMBL; AK175675; BAD43438.1; -; mRNA.
DR EMBL; AK176204; BAD43967.1; -; mRNA.
DR EMBL; AK176400; BAD44163.1; -; mRNA.
DR EMBL; AK176502; BAD44265.1; -; mRNA.
DR EMBL; AY087581; AAM65123.1; -; mRNA.
DR RefSeq; NP_566703.4; NM_113122.5.
DR AlphaFoldDB; Q9LHJ3; -.
DR STRING; 3702.AT3G22240.1; -.
DR PaxDb; Q9LHJ3; -.
DR PRIDE; Q9LHJ3; -.
DR ProteomicsDB; 191462; -.
DR EnsemblPlants; AT3G22240.1; AT3G22240.1; AT3G22240.
DR GeneID; 821794; -.
DR Gramene; AT3G22240.1; AT3G22240.1; AT3G22240.
DR KEGG; ath:AT3G22240; -.
DR Araport; AT3G22240; -.
DR TAIR; locus:2091623; AT3G22240.
DR eggNOG; ENOG502S924; Eukaryota.
DR HOGENOM; CLU_128451_2_2_1; -.
DR InParanoid; Q9LHJ3; -.
DR OMA; NPSEQNH; -.
DR OrthoDB; 1607719at2759; -.
DR PhylomeDB; Q9LHJ3; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LHJ3; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR GO; GO:0005886; C:plasma membrane; IDA:UniProtKB.
DR InterPro; IPR028144; CYSTM_dom.
DR InterPro; IPR044850; WIH2-like.
DR PANTHER; PTHR31568; PTHR31568; 1.
DR Pfam; PF12734; CYSTM; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Membrane; Nucleus; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..72
FT /note="Protein CYSTEINE-RICH TRANSMEMBRANE MODULE 9"
FT /id="PRO_0000454806"
FT TRANSMEM 49..65
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 72 AA; 7525 MW; 8415E09449228599 CRC64;
MNPSEQNHLS VEKPSQTSSG PYTSPPPIGY PTRDAMVGDP PAAAVETKSK GDGFWKGCCA
AICCCCVLDA CF
