CSTR3_ORYSI
ID CSTR3_ORYSI Reviewed; 402 AA.
AC B8A7Q8;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 03-MAR-2009, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=CMP-sialic acid transporter 3 {ECO:0000305};
DE Short=CMP-SA-Tr 3 {ECO:0000305};
DE Short=CMP-Sia-Tr 3 {ECO:0000305};
DE AltName: Full=CMP-sialic acid transporter-like protein 3 {ECO:0000305};
GN Name=CSTLP3 {ECO:0000305};
GN ORFNames=OsI_04797 {ECO:0000312|EMBL:EEC71963.1};
OS Oryza sativa subsp. indica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39946;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. 93-11;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
CC -!- FUNCTION: Sugar transporter involved in the transport of CMP-sialic
CC acid from the cytoplasm into the Golgi. May transport important
CC nucleotide sugars such as CMP-Kdo (2-keto-3-deoxy-D-manno-octulosonic
CC acid) in physiological conditions. {ECO:0000250|UniProtKB:Q654D9}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. CMP-
CC Sialate:CMP antiporter (TC 2.A.7.12) subfamily. {ECO:0000305}.
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DR EMBL; CM000126; EEC71963.1; -; Genomic_DNA.
DR AlphaFoldDB; B8A7Q8; -.
DR SMR; B8A7Q8; -.
DR STRING; 39946.B8A7Q8; -.
DR iPTMnet; B8A7Q8; -.
DR EnsemblPlants; BGIOSGA004987-TA; BGIOSGA004987-PA; BGIOSGA004987.
DR Gramene; BGIOSGA004987-TA; BGIOSGA004987-PA; BGIOSGA004987.
DR HOGENOM; CLU_035460_0_0_1; -.
DR OMA; CLYCREN; -.
DR Proteomes; UP000007015; Chromosome 1.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR PANTHER; PTHR10231; PTHR10231; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..402
FT /note="CMP-sialic acid transporter 3"
FT /id="PRO_0000434342"
FT TOPO_DOM 1..42
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 64..73
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 95..118
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 140..146
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 168..170
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 171..191
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 192..202
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 203..223
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 224..243
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 244..264
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 265..280
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 281..301
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 302..321
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 322..342
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 343..402
FT /note="Lumenal"
FT /evidence="ECO:0000305"
SQ SEQUENCE 402 AA; 44226 MW; CC629DFE2C95EC62 CRC64;
MSGEVECRVC HAKVQVPMAA AAVSKAYDIH RSSVSSRQRA LNVLLVSGDC VLAGLQPILV
YMCKVDGKFK FSPVSVNFLT EITKIIFAII MLCIQARRLK VGEKPFLTVS TFMQAARNNV
LLAVPALFYA INNYMKFVMQ LYFNPATVKM LGNLKVLVIA VLLKVIMRRR FSTIQWEALA
LLLIGISVNQ LKSLPEGSST LGLPVAAGAY LYTLFFVTVP ALASVYNEKA LKSQFDTSIY
LQNLFLYGYG AIFNFLGLVI TAIIQGPSSF NILEGHSKAT MFLICNNAAQ GILSSFFFKY
ADTILKKYSS TIATIFTGVA SAVLFGHTLT INFVLAISIV IISMHQYLSN QIKDEVPSSK
IEMGDAHEHR SKESVVVNVS DSIATEAKHR HGTDERQPLL PV
