CSTR5_ORYSJ
ID CSTR5_ORYSJ Reviewed; 405 AA.
AC Q6K8S7; A0A0P0VLP3; B7EH62;
DT 14-OCT-2015, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=CMP-sialic acid transporter 5 {ECO:0000305};
DE Short=CMP-SA-Tr 5 {ECO:0000305};
DE Short=CMP-Sia-Tr 5 {ECO:0000305};
DE AltName: Full=CMP-sialic acid transporter-like protein 5 {ECO:0000305};
GN Name=CSTLP5 {ECO:0000305};
GN OrderedLocusNames=Os02g0604300 {ECO:0000312|EMBL:BAF09282.1},
GN LOC_Os02g39200 {ECO:0000305};
GN ORFNames=OJ1058_F07.2 {ECO:0000312|EMBL:BAD19315.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
CC -!- FUNCTION: Sugar transporter involved in the transport of CMP-sialic
CC acid from the cytoplasm into the Golgi. May transport important
CC nucleotide sugars such as CMP-Kdo (2-keto-3-deoxy-D-manno-octulosonic
CC acid) in physiological conditions. {ECO:0000250|UniProtKB:Q654D9}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000305}; Multi-
CC pass membrane protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the nucleotide-sugar transporter family. CMP-
CC Sialate:CMP antiporter (TC 2.A.7.12) subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAG91709.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AP004111; BAD19315.1; -; Genomic_DNA.
DR EMBL; AP008208; BAF09282.1; -; Genomic_DNA.
DR EMBL; AP014958; BAS79647.1; -; Genomic_DNA.
DR EMBL; AK069982; BAG91709.1; ALT_INIT; mRNA.
DR RefSeq; XP_015622898.1; XM_015767412.1.
DR AlphaFoldDB; Q6K8S7; -.
DR SMR; Q6K8S7; -.
DR STRING; 4530.OS02T0604300-01; -.
DR PaxDb; Q6K8S7; -.
DR PRIDE; Q6K8S7; -.
DR EnsemblPlants; Os02t0604300-01; Os02t0604300-01; Os02g0604300.
DR GeneID; 4329914; -.
DR Gramene; Os02t0604300-01; Os02t0604300-01; Os02g0604300.
DR KEGG; osa:4329914; -.
DR eggNOG; KOG2234; Eukaryota.
DR HOGENOM; CLU_035460_0_0_1; -.
DR InParanoid; Q6K8S7; -.
DR OMA; SSCVVMI; -.
DR OrthoDB; 754910at2759; -.
DR Proteomes; UP000000763; Chromosome 2.
DR Proteomes; UP000059680; Chromosome 2.
DR Genevisible; Q6K8S7; OS.
DR GO; GO:0030173; C:integral component of Golgi membrane; IBA:GO_Central.
DR GO; GO:0015165; F:pyrimidine nucleotide-sugar transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.
DR InterPro; IPR007271; Nuc_sug_transpt.
DR PANTHER; PTHR10231; PTHR10231; 1.
DR Pfam; PF04142; Nuc_sug_transp; 1.
DR PIRSF; PIRSF005799; UDP-gal_transpt; 1.
PE 2: Evidence at transcript level;
KW Golgi apparatus; Membrane; Reference proteome; Sugar transport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..405
FT /note="CMP-sialic acid transporter 5"
FT /id="PRO_0000434345"
FT TOPO_DOM 1..43
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 44..64
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 65..74
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 75..95
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 96..121
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 143..147
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 148..168
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 169..171
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 172..192
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 193..200
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 201..221
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 222..244
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 245..265
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 266..281
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT TRANSMEM 282..302
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 303..322
FT /note="Cytoplasmic"
FT /evidence="ECO:0000305"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 344..405
FT /note="Lumenal"
FT /evidence="ECO:0000305"
FT REGION 368..405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 405 AA; 44888 MW; CF6F4E40296876D5 CRC64;
MQRNGVVECS VCRSRLVVPS PRSVSRAYDK HRSKISSKFR ALNVLLVVGD CILVGLQPIL
VFMSKVDGKF QFSPISVNFL TEVTKVVFAI VMLIIQSRKQ KVGEKPLLAR STFIQAARNN
ALLAVPALLY AINNYLKFIM QLYFNPSTVK MLSNLKVLVI AVLLKFIMKR RFSVIQWEAL
ALLLIGISIN QLRTVPAGNT AFGLPVTAIA YIYTLIFVTV PSLASVYNEY ALKSQYDTSI
YLQNLFLYGY GAIFNFLGIL GTALFQGPES FNILRGHSRA TMFLICNNAA QGILSSFFFK
YADTILKKYS STVATIFTGL ASAAFLGHTL TINFLLGISV VFISMHQFFS PLAKAKDDKP
AELLELEDTQ NHRSSESSFV NMTAGAAEDA SHRIGTDERQ PLLPT
