CT085_HUMAN
ID CT085_HUMAN Reviewed; 137 AA.
AC Q9H1P6;
DT 10-JAN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Uncharacterized protein C20orf85;
GN Name=C20orf85;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11780052; DOI=10.1038/414865a;
RA Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 20.";
RL Nature 414:865-871(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q9H1P6; Q08043: ACTN3; NbExp=3; IntAct=EBI-12155483, EBI-2880652;
CC Q9H1P6; Q9BT30: ALKBH7; NbExp=3; IntAct=EBI-12155483, EBI-2878075;
CC Q9H1P6; Q86U10: ASPG; NbExp=3; IntAct=EBI-12155483, EBI-19946665;
CC Q9H1P6; Q9NPB3: CABP2; NbExp=3; IntAct=EBI-12155483, EBI-12011224;
CC Q9H1P6; P54284: CACNB3; NbExp=3; IntAct=EBI-12155483, EBI-1184651;
CC Q9H1P6; O14936-4: CASK; NbExp=3; IntAct=EBI-12155483, EBI-12007726;
CC Q9H1P6; Q9NZN8: CNOT2; NbExp=3; IntAct=EBI-12155483, EBI-743033;
CC Q9H1P6; Q86UW9: DTX2; NbExp=3; IntAct=EBI-12155483, EBI-740376;
CC Q9H1P6; Q5JVL4: EFHC1; NbExp=3; IntAct=EBI-12155483, EBI-743105;
CC Q9H1P6; Q14192: FHL2; NbExp=3; IntAct=EBI-12155483, EBI-701903;
CC Q9H1P6; O95198: KLHL2; NbExp=3; IntAct=EBI-12155483, EBI-746999;
CC Q9H1P6; Q9BS75: KLHL20; NbExp=3; IntAct=EBI-12155483, EBI-10693436;
CC Q9H1P6; Q3LI70: KRTAP19-6; NbExp=3; IntAct=EBI-12155483, EBI-12805508;
CC Q9H1P6; Q9BYR8: KRTAP3-1; NbExp=3; IntAct=EBI-12155483, EBI-9996449;
CC Q9H1P6; Q3LI66: KRTAP6-2; NbExp=3; IntAct=EBI-12155483, EBI-11962084;
CC Q9H1P6; Q8IUC2: KRTAP8-1; NbExp=3; IntAct=EBI-12155483, EBI-10261141;
CC Q9H1P6; P80188: LCN2; NbExp=3; IntAct=EBI-12155483, EBI-11911016;
CC Q9H1P6; Q9UI95: MAD2L2; NbExp=3; IntAct=EBI-12155483, EBI-77889;
CC Q9H1P6; O43482: OIP5; NbExp=3; IntAct=EBI-12155483, EBI-536879;
CC Q9H1P6; Q99471: PFDN5; NbExp=3; IntAct=EBI-12155483, EBI-357275;
CC Q9H1P6; Q93062-3: RBPMS; NbExp=3; IntAct=EBI-12155483, EBI-740343;
CC Q9H1P6; Q6DKK2: TTC19; NbExp=3; IntAct=EBI-12155483, EBI-948354;
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DR EMBL; AL354776; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC035405; AAH35405.1; -; mRNA.
DR CCDS; CCDS13465.1; -.
DR RefSeq; NP_848551.1; NM_178456.2.
DR AlphaFoldDB; Q9H1P6; -.
DR SMR; Q9H1P6; -.
DR BioGRID; 126134; 27.
DR IntAct; Q9H1P6; 22.
DR STRING; 9606.ENSP00000360210; -.
DR iPTMnet; Q9H1P6; -.
DR PhosphoSitePlus; Q9H1P6; -.
DR BioMuta; C20orf85; -.
DR MassIVE; Q9H1P6; -.
DR PaxDb; Q9H1P6; -.
DR PeptideAtlas; Q9H1P6; -.
DR PRIDE; Q9H1P6; -.
DR Antibodypedia; 70475; 12 antibodies from 5 providers.
DR DNASU; 128602; -.
DR Ensembl; ENST00000371168.4; ENSP00000360210.3; ENSG00000124237.6.
DR GeneID; 128602; -.
DR KEGG; hsa:128602; -.
DR MANE-Select; ENST00000371168.4; ENSP00000360210.3; NM_178456.3; NP_848551.1.
DR UCSC; uc002xyv.4; human.
DR CTD; 128602; -.
DR DisGeNET; 128602; -.
DR GeneCards; C20orf85; -.
DR HGNC; HGNC:16216; C20orf85.
DR HPA; ENSG00000124237; Tissue enriched (fallopian).
DR MIM; 619277; gene.
DR neXtProt; NX_Q9H1P6; -.
DR OpenTargets; ENSG00000124237; -.
DR PharmGKB; PA25793; -.
DR VEuPathDB; HostDB:ENSG00000124237; -.
DR eggNOG; ENOG502S4TU; Eukaryota.
DR GeneTree; ENSGT00940000154459; -.
DR HOGENOM; CLU_125517_0_0_1; -.
DR InParanoid; Q9H1P6; -.
DR OMA; WPEQGIH; -.
DR OrthoDB; 1412686at2759; -.
DR PhylomeDB; Q9H1P6; -.
DR TreeFam; TF329228; -.
DR PathwayCommons; Q9H1P6; -.
DR SignaLink; Q9H1P6; -.
DR BioGRID-ORCS; 128602; 36 hits in 1040 CRISPR screens.
DR GenomeRNAi; 128602; -.
DR Pharos; Q9H1P6; Tdark.
DR PRO; PR:Q9H1P6; -.
DR Proteomes; UP000005640; Chromosome 20.
DR RNAct; Q9H1P6; protein.
DR Bgee; ENSG00000124237; Expressed in bronchial epithelial cell and 77 other tissues.
DR Genevisible; Q9H1P6; HS.
DR InterPro; IPR020339; Uncharacterised_C20orf85.
DR Pfam; PF14945; LLC1; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..137
FT /note="Uncharacterized protein C20orf85"
FT /id="PRO_0000079448"
FT VARIANT 26
FT /note="R -> H (in dbSNP:rs16984945)"
FT /id="VAR_033759"
FT VARIANT 34
FT /note="R -> Q (in dbSNP:rs45576936)"
FT /id="VAR_061632"
FT VARIANT 99
FT /note="I -> V (in dbSNP:rs17440813)"
FT /id="VAR_033760"
SQ SEQUENCE 137 AA; 15719 MW; 9EDB8FF6FA3CD923 CRC64;
MAQKPLSTAA AERMNLVGQD EIWKYRLKAE SEARQNWPQN WGFLTTPFEE LIKCEEDLPT
PKPKIELPER FRIRPVTPVE KYIKVFPSPP VPQTTQGFIG WRSAVPGLNK CLELDDAIRS
CKGAFARELC WPKQGVH
