CT10C_CONAO
ID CT10C_CONAO Reviewed; 11 AA.
AC C0HKY4;
DT 27-SEP-2017, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2017, sequence version 1.
DT 22-APR-2020, entry version 8.
DE RecName: Full=Conotoxin ar5c {ECO:0000303|PubMed:26100663};
OS Conus araneosus (Cobweb cone).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Conus.
OX NCBI_TaxID=101286 {ECO:0000303|PubMed:26100663};
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, SUBCELLULAR LOCATION, MASS SPECTROMETRY, AND
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC TISSUE=Venom {ECO:0000303|PubMed:26100663};
RX PubMed=26100663; DOI=10.1016/j.toxicon.2015.06.017;
RA Franklin J.B., Rajesh R.P.;
RT "A sleep-inducing peptide from the venom of the Indian cone snail Conus
RT araneosus.";
RL Toxicon 103:39-47(2015).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:26100663}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC {ECO:0000305|PubMed:26100663}.
CC -!- DOMAIN: The cysteine framework is X (CC-C-C).
CC {ECO:0000303|PubMed:26100663}.
CC -!- MASS SPECTROMETRY: Mass=1260.6; Method=MALDI;
CC Evidence={ECO:0000269|PubMed:26100663};
CC -!- SIMILARITY: Belongs to the conotoxin T superfamily. {ECO:0000305}.
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DR GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT PEPTIDE 1..11
FT /note="Conotoxin ar5c"
FT /evidence="ECO:0000269|PubMed:26100663"
FT /id="PRO_0000441660"
FT DISULFID 2..11
FT /evidence="ECO:0000250|UniProtKB:P0CI23"
FT DISULFID 3..8
FT /evidence="ECO:0000250|UniProtKB:P0CI23"
FT UNSURE 7
FT /note="I or L"
FT /evidence="ECO:0000303|PubMed:26100663"
SQ SEQUENCE 11 AA; 1266 MW; D27AA45BB0532B42 CRC64;
ACCVYKICYP C