CT144_HUMAN
ID CT144_HUMAN Reviewed; 153 AA.
AC Q9BQM9; Q1AHR2;
DT 19-OCT-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Uncharacterized protein C20orf144;
DE AltName: Full=Bcl-2-like protein from testis;
DE Short=Bclt;
GN Name=C20orf144;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RA O'Doherty A.M., Zheng H., Wang S., Esaki Y., Yan W.;
RT "Bclt is a novel Bcl-2 family protein preferentially expressed in the
RT testis.";
RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11780052; DOI=10.1038/414865a;
RA Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P.,
RA Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J., Buck D., Burrill W.D.,
RA Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G.,
RA Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E.,
RA Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D.,
RA Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M.,
RA Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D.,
RA Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M.,
RA Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A.,
RA Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L.,
RA Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L.,
RA Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.;
RT "The DNA sequence and comparative analysis of human chromosome 20.";
RL Nature 414:865-871(2001).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- TISSUE SPECIFICITY: Preferentially expressed in the testis.
CC {ECO:0000269|Ref.1}.
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DR EMBL; DQ080434; AAZ39562.1; -; mRNA.
DR EMBL; AL121906; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471077; EAW76310.1; -; Genomic_DNA.
DR EMBL; BC032818; AAH32818.1; -; mRNA.
DR CCDS; CCDS13223.1; -.
DR RefSeq; NP_543015.1; NM_080825.3.
DR AlphaFoldDB; Q9BQM9; -.
DR STRING; 9606.ENSP00000364370; -.
DR iPTMnet; Q9BQM9; -.
DR PhosphoSitePlus; Q9BQM9; -.
DR BioMuta; C20orf144; -.
DR DMDM; 24211595; -.
DR MassIVE; Q9BQM9; -.
DR PaxDb; Q9BQM9; -.
DR PeptideAtlas; Q9BQM9; -.
DR PRIDE; Q9BQM9; -.
DR ProteomicsDB; 78701; -.
DR Antibodypedia; 43039; 57 antibodies from 14 providers.
DR DNASU; 128864; -.
DR Ensembl; ENST00000375222.4; ENSP00000364370.3; ENSG00000149609.6.
DR GeneID; 128864; -.
DR KEGG; hsa:128864; -.
DR MANE-Select; ENST00000375222.4; ENSP00000364370.3; NM_080825.4; NP_543015.1.
DR UCSC; uc002wzs.3; human.
DR CTD; 128864; -.
DR GeneCards; C20orf144; -.
DR HGNC; HGNC:16137; C20orf144.
DR HPA; ENSG00000149609; Tissue enriched (testis).
DR neXtProt; NX_Q9BQM9; -.
DR OpenTargets; ENSG00000149609; -.
DR PharmGKB; PA25687; -.
DR VEuPathDB; HostDB:ENSG00000149609; -.
DR eggNOG; ENOG502T9GG; Eukaryota.
DR GeneTree; ENSGT00390000013020; -.
DR HOGENOM; CLU_128811_0_0_1; -.
DR InParanoid; Q9BQM9; -.
DR OMA; DKAWWRQ; -.
DR OrthoDB; 1365595at2759; -.
DR PhylomeDB; Q9BQM9; -.
DR TreeFam; TF338219; -.
DR PathwayCommons; Q9BQM9; -.
DR BioGRID-ORCS; 128864; 14 hits in 1035 CRISPR screens.
DR GenomeRNAi; 128864; -.
DR Pharos; Q9BQM9; Tdark.
DR PRO; PR:Q9BQM9; -.
DR Proteomes; UP000005640; Chromosome 20.
DR RNAct; Q9BQM9; protein.
DR Bgee; ENSG00000149609; Expressed in right testis and 98 other tissues.
DR Genevisible; Q9BQM9; HS.
DR InterPro; IPR029296; Bcl-2-like_put.
DR PANTHER; PTHR37335; PTHR37335; 1.
DR Pfam; PF15318; Bclt; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..153
FT /note="Uncharacterized protein C20orf144"
FT /id="PRO_0000079467"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..94
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 125..153
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 62
FT /note="Q -> R (in dbSNP:rs7260921)"
FT /id="VAR_050921"
SQ SEQUENCE 153 AA; 17214 MW; 70209AA2A474E5F0 CRC64;
MGNYSSHKRT KAPKQARKER PADMDKAWWK SFLNHLTRKK PATRIVLILP LDKRQPLANA
GQRIDYASGA GLGSPAAPRL RGAGEGSERE PRMPVLLLLR RQEARRPEEG GARAALSWPR
LLSRFRSPGK APREAGPAEE QPRKRCRCPR PQL
