CT18_HUMAN
ID CT18_HUMAN Reviewed; 33 AA.
AC P0C5K6;
DT 23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 33.
DE RecName: Full=Putative tumor antigen NA88-A;
DE AltName: Full=Cancer/testis antigen 18;
DE Short=CT18;
GN Name=VENTXP1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND IDENTIFICATION AS A
RP CANCER/TESTIS ANTIGEN.
RX PubMed=10790436; DOI=10.1084/jem.191.9.1617;
RA Moreau-Aubry A., Le Guiner S., Labarriere N., Gesnel M.-C., Jotereau F.,
RA Breathnach R.;
RT "A processed pseudogene codes for a new antigen recognized by a CD8(+) T
RT cell clone on melanoma.";
RL J. Exp. Med. 191:1617-1624(2000).
CC -!- TISSUE SPECIFICITY: Expressed in testis and melanoma cell lines.
CC {ECO:0000269|PubMed:10790436}.
CC -!- CAUTION: Could be the product of a pseudogene. This peptide sequence
CC originates from a processed pseudogene derived from a retro-transcript
CC of the mRNA coding for VENTX. The protein sequence is translated from a
CC region that corresponds to the 3'-UTR of the original gene.
CC {ECO:0000305}.
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DR EMBL; AF164963; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; P0C5K6; -.
DR BioMuta; HGNC:30900; -.
DR PRIDE; P0C5K6; -.
DR GeneCards; VENTXP1; -.
DR HGNC; HGNC:30900; VENTXP1.
DR neXtProt; NX_P0C5K6; -.
DR InParanoid; P0C5K6; -.
DR Pharos; P0C5K6; Tdark.
DR Proteomes; UP000005640; Unplaced.
PE 5: Uncertain;
KW Reference proteome.
FT CHAIN 1..33
FT /note="Putative tumor antigen NA88-A"
FT /id="PRO_0000308923"
SQ SEQUENCE 33 AA; 3500 MW; F4A5BAA0743183DD CRC64;
MSPPSSMCSP VPLLAAASGQ NRMTQGQHFL QKV