ID   CT1BA_BACTW             Reviewed;         265 AA.
AC   Q45790;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Type-1Ba cytolytic delta-endotoxin;
GN   Name=cyt1Ba1;
OS   Bacillus thuringiensis subsp. neoleoensis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=43262;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=PS201T6;
RA   Narva K.E., Payne J.M., Uyeda K.A., Stalder C.J., Michaels T.E.;
RL   Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Kills the larvae of dipteran insects by making pores in the
CC       epithelial cell membrane of the insect midgut. {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: The crystal protein is produced during sporulation
CC       and is accumulated both as an inclusion and as part of the spore coat.
CC   -!- PTM: Active after proteolytic processing. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the cyt1/cyt2 endotoxin family. {ECO:0000305}.
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DR   EMBL; U37196; AAB03693.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q45790; -.
DR   SMR; Q45790; -.
DR   GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.198.10; -; 1.
DR   InterPro; IPR035918; CytB_endotoxin-like_sf.
DR   InterPro; IPR001615; Endotoxin_CytB.
DR   Pfam; PF01338; Bac_thur_toxin; 1.
DR   SUPFAM; SSF55676; SSF55676; 1.
PE   2: Evidence at transcript level;
KW   Sporulation; Toxin; Virulence.
FT   CHAIN           1..265
FT                   /note="Type-1Ba cytolytic delta-endotoxin"
FT                   /id="PRO_0000174107"
SQ   SEQUENCE   265 AA;  29906 MW;  260D1495F8C477A2 CRC64;
     MKESIYYNEE NEIQISQGNC FPEELGHNPW RQPQSTARVI YLKVKDPIDT TQLLEITEIE
     NPNYVLQAIQ LAAAFQDALV PTETEFGEAI RFSMPKGLEV AKTIQPKGAV VAYTDQTLSQ
     SNNQVSVMID RVISVLKTVM GVALSGSIIT QLTAAITDTF TNLNTQKDSA WVFWGKETSH
     QTNYTYNVMF AIQNETTGRV MMCVPIGFEI RVFTDKRTVL FLTTKDYANY SVNIQTLRFA
     QPLIDSRALS INDLSEALRS SKYLY