ID   CT274_CONMO             Reviewed;          11 AA.
AC   P0C2F2;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 1.
DT   22-APR-2020, entry version 26.
DE   RecName: Full=Conotoxin Mo1274 {ECO:0000303|PubMed:17134143};
OS   Conus monile (Necklace cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Strategoconus.
OX   NCBI_TaxID=351660;
RN   [1]
RP   PROTEIN SEQUENCE, SUBCELLULAR LOCATION, MASS SPECTROMETRY, DISULFIDE BONDS,
RP   AND BROMINATION AT TRP-3.
RC   TISSUE=Venom;
RX   PubMed=17134143; DOI=10.1021/ac0607764;
RA   Nair S.S., Nilsson C.L., Emmett M.R., Schaub T.M., Gowd K.H., Thakur S.S.,
RA   Krishnan K.S., Balaram P., Marshall A.G.;
RT   "De novo sequencing and disulfide mapping of a bromotryptophan-containing
RT   conotoxin by Fourier transform ion cyclotron resonance mass spectrometry.";
RL   Anal. Chem. 78:8082-8088(2006).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17134143}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:17134143}.
CC   -!- DOMAIN: The cysteine framework is V (CC-CC).
CC   -!- MASS SPECTROMETRY: Mass=1274.32; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:17134143};
CC   -!- SIMILARITY: Belongs to the conotoxin T superfamily. {ECO:0000305}.
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DR   ConoServer; 1617; Mo1274.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Bromination; Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   PEPTIDE         1..11
FT                   /note="Conotoxin Mo1274"
FT                   /id="PRO_0000274073"
FT   MOD_RES         3
FT                   /note="6'-bromotryptophan"
FT                   /evidence="ECO:0000269|PubMed:17134143"
FT   DISULFID        4..10
FT                   /evidence="ECO:0000269|PubMed:17134143"
FT   DISULFID        5..11
FT                   /evidence="ECO:0000269|PubMed:17134143"
SQ   SEQUENCE   11 AA;  1201 MW;  8229034F0DC5BEBE CRC64;
     GNWCCSARVC C