ID   CT361_CONVR             Reviewed;          12 AA.
AC   P0C642;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-JAN-2008, sequence version 1.
DT   22-APR-2020, entry version 24.
DE   RecName: Full=Conotoxin Vi1361 {ECO:0000303|PubMed:17544293};
DE   AltName: Full=Conotoxin Vi1360 {ECO:0000303|PubMed:20843009};
OS   Conus virgo (Virgin cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Virgiconus.
OX   NCBI_TaxID=89427;
RN   [1]
RP   PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AMIDATION AT ILE-12,
RP   DISULFIDE BONDS, MASS SPECTROMETRY, AND SUBCELLULAR LOCATION.
RC   TISSUE=Venom;
RX   PubMed=17544293; DOI=10.1016/j.jasms.2007.04.009;
RA   Mandal A.K., Ramasamy M.R.S., Sabareesh V., Openshaw M.E., Krishnan K.S.,
RA   Balaram P.;
RT   "Sequencing of T-superfamily conotoxins from Conus virgo: pyroglutamic acid
RT   identification and disulfide arrangement by MALDI mass spectrometry.";
RL   J. Am. Soc. Mass Spectrom. 18:1396-1404(2007).
RN   [2]
RP   PROTEIN SEQUENCE, DISULFIDE BONDS, PYROGLUTAMATE FORMATION AT GLN-1,
RP   AMIDATION AT ILE-12, IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR
RP   LOCATION.
RC   TISSUE=Venom;
RX   PubMed=20843009; DOI=10.1021/ac101867e;
RA   Gupta K., Kumar M., Balaram P.;
RT   "Disulfide bond assignments by mass spectrometry of native natural
RT   peptides: cysteine pairing in disulfide bonded conotoxins.";
RL   Anal. Chem. 82:8313-8319(2010).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:17544293,
CC       ECO:0000269|PubMed:20843009}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:17544293, ECO:0000305|PubMed:20843009}.
CC   -!- DOMAIN: The cysteine framework is V (CC-CC). {ECO:0000305}.
CC   -!- MASS SPECTROMETRY: Mass=1360.6; Method=Electrospray;
CC       Evidence={ECO:0000269|PubMed:17544293};
CC   -!- SIMILARITY: Belongs to the conotoxin T superfamily. {ECO:0000305}.
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DR   ConoServer; 2788; Vi1361.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond;
KW   Pyrrolidone carboxylic acid; Secreted; Toxin.
FT   PEPTIDE         1..12
FT                   /note="Conotoxin Vi1361"
FT                   /evidence="ECO:0000269|PubMed:17544293,
FT                   ECO:0000269|PubMed:20843009"
FT                   /id="PRO_0000315455"
FT   MOD_RES         1
FT                   /note="Pyrrolidone carboxylic acid"
FT                   /evidence="ECO:0000269|PubMed:17544293,
FT                   ECO:0000269|PubMed:20843009"
FT   MOD_RES         12
FT                   /note="Isoleucine amide"
FT                   /evidence="ECO:0000269|PubMed:17544293,
FT                   ECO:0000269|PubMed:20843009"
FT   DISULFID        2..9
FT                   /evidence="ECO:0000269|PubMed:20843009"
FT   DISULFID        3..10
FT                   /evidence="ECO:0000269|PubMed:20843009"
SQ   SEQUENCE   12 AA;  1384 MW;  9106D375EE076681 CRC64;
     QCCPTMPECC RI