CT457_HUMAN
ID CT457_HUMAN Reviewed; 189 AA.
AC P0DMV0;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 27-MAY-2015, sequence version 1.
DT 03-AUG-2022, entry version 34.
DE RecName: Full=Cancer/testis antigen family 45 member A7 {ECO:0000312|HGNC:HGNC:51260};
DE AltName: Full=Cancer/testis antigen 45A7 {ECO:0000305};
GN Name=CT45A7 {ECO:0000312|HGNC:HGNC:51260};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
CC -!- SIMILARITY: Belongs to the CT45 family.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC240441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS76032.1; -.
DR RefSeq; NP_001007552.2; NM_001007551.4.
DR RefSeq; NP_001017438.2; NM_001017438.2.
DR RefSeq; NP_001165759.2; NM_001172288.2.
DR RefSeq; NP_001278472.1; NM_001291543.1.
DR RefSeq; XP_003960131.1; XM_003960082.4.
DR RefSeq; XP_005262482.2; XM_005262425.4.
DR RefSeq; XP_011529531.1; XM_011531229.2.
DR RefSeq; XP_011529643.1; XM_011531341.2.
DR RefSeq; XP_011529653.1; XM_011531351.1.
DR AlphaFoldDB; P0DMV0; -.
DR SMR; P0DMV0; -.
DR IntAct; P0DMV0; 1.
DR iPTMnet; P0DMV0; -.
DR PhosphoSitePlus; P0DMV0; -.
DR BioMuta; CT45A7; -.
DR jPOST; P0DMV0; -.
DR MassIVE; P0DMV0; -.
DR Antibodypedia; 80868; 1 antibodies from 1 providers.
DR DNASU; 441521; -.
DR Ensembl; ENST00000610598.5; ENSP00000482241.1; ENSG00000273696.5.
DR Ensembl; ENST00000620885.1; ENSP00000480765.1; ENSG00000273696.5.
DR GeneID; 101060211; -.
DR GeneID; 441521; -.
DR GeneID; 541465; -.
DR KEGG; hsa:101060211; -.
DR KEGG; hsa:441521; -.
DR KEGG; hsa:541465; -.
DR MANE-Select; ENST00000610598.5; ENSP00000482241.1; NM_001394668.1; NP_001381597.1.
DR MANE-Select; ENST00000620654.2; ENSP00000479608.2; NM_001017438.3; NP_001017438.2.
DR CTD; 101060211; -.
DR CTD; 441521; -.
DR CTD; 541465; -.
DR GeneCards; CT45A7; -.
DR HGNC; HGNC:51260; CT45A7.
DR HPA; ENSG00000273696; Not detected.
DR neXtProt; NX_P0DMV0; -.
DR OpenTargets; ENSG00000228836; -.
DR OpenTargets; ENSG00000278289; -.
DR VEuPathDB; HostDB:ENSG00000273696; -.
DR GeneTree; ENSGT00390000016655; -.
DR OMA; RIFKFEG; -.
DR OrthoDB; 1187027at2759; -.
DR PhylomeDB; P0DMV0; -.
DR PathwayCommons; P0DMV0; -.
DR SignaLink; P0DMV0; -.
DR BioGRID-ORCS; 101060211; 8 hits in 75 CRISPR screens.
DR BioGRID-ORCS; 441521; 6 hits in 611 CRISPR screens.
DR BioGRID-ORCS; 541465; 5 hits in 183 CRISPR screens.
DR Pharos; P0DMV0; Tdark.
DR PRO; PR:P0DMV0; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; P0DMV0; protein.
DR Bgee; ENSG00000273696; Expressed in apex of heart and 41 other tissues.
DR GO; GO:0032039; C:integrator complex; IBA:GO_Central.
DR GO; GO:0034472; P:snRNA 3'-end processing; IBA:GO_Central.
DR InterPro; IPR029307; INT_SG_DDX_CT_C.
DR Pfam; PF15300; INT_SG_DDX_CT_C; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..189
FT /note="Cancer/testis antigen family 45 member A7"
FT /id="PRO_0000433029"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 82..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 92..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 189 AA; 21232 MW; 202C0D8DB6D6F042 CRC64;
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS AMSKEKKLMT
GHAIPPSQLD SQIDDFTGFS KDGMMQKPGS NAPVGGNVTS SFSGDDLECR ETASSPKSQR
EINADIKRKL VKELRCVGQK YEKIFEMLEG VQGPTAVRKR FFESIIKEAA RCMRRDFVKH
LKKKLKRMI
