CT45A_HUMAN
ID CT45A_HUMAN Reviewed; 189 AA.
AC P0DMU9; A8K842; B7ZMC5; Q6NSH3;
DT 27-MAY-2015, integrated into UniProtKB/Swiss-Prot.
DT 27-MAY-2015, sequence version 1.
DT 03-AUG-2022, entry version 39.
DE RecName: Full=Cancer/testis antigen family 45 member A10 {ECO:0000312|HGNC:HGNC:51263};
DE AltName: Full=Cancer/testis antigen 45A10 {ECO:0000305};
GN Name=CT45A10 {ECO:0000312|HGNC:HGNC:51263};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC P0DMU9; Q5HYN5: CT45A1; NbExp=3; IntAct=EBI-12153495, EBI-12051833;
CC P0DMU9; P0DMU9: CT45A10; NbExp=3; IntAct=EBI-12153495, EBI-12153495;
CC P0DMU9; Q92997: DVL3; NbExp=3; IntAct=EBI-12153495, EBI-739789;
CC P0DMU9; O00560: SDCBP; NbExp=6; IntAct=EBI-12153495, EBI-727004;
CC P0DMU9; Q9H190: SDCBP2; NbExp=3; IntAct=EBI-12153495, EBI-742426;
CC -!- SIMILARITY: Belongs to the CT45 family.
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DR EMBL; AK292207; BAF84896.1; -; mRNA.
DR EMBL; AC240441; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC070138; AAH70138.1; -; mRNA.
DR EMBL; BC144429; AAI44430.1; -; mRNA.
DR EMBL; BC144430; AAI44431.1; -; mRNA.
DR EMBL; BC144527; AAI44528.1; -; mRNA.
DR EMBL; BC144528; AAI44529.1; -; mRNA.
DR CCDS; CCDS76035.1; -.
DR RefSeq; NP_001278456.1; NM_001291527.1.
DR RefSeq; NP_001278457.1; NM_001291528.1.
DR RefSeq; NP_001278458.1; NM_001291529.1.
DR RefSeq; NP_001278459.1; NM_001291530.1.
DR RefSeq; XP_011529540.1; XM_011531238.2.
DR RefSeq; XP_011529541.1; XM_011531239.1.
DR AlphaFoldDB; P0DMU9; -.
DR SMR; P0DMU9; -.
DR IntAct; P0DMU9; 4.
DR STRING; 9606.ENSP00000484601; -.
DR iPTMnet; P0DMU9; -.
DR PhosphoSitePlus; P0DMU9; -.
DR BioMuta; CT45A10; -.
DR jPOST; P0DMU9; -.
DR MassIVE; P0DMU9; -.
DR PaxDb; P0DMU9; -.
DR PeptideAtlas; P0DMU9; -.
DR PRIDE; P0DMU9; -.
DR Antibodypedia; 75747; 2 antibodies from 2 providers.
DR DNASU; 102723631; -.
DR Ensembl; ENST00000611668.4; ENSP00000484601.1; ENSG00000269586.8.
DR Ensembl; ENST00000617981.1; ENSP00000481558.1; ENSG00000269586.8.
DR Ensembl; ENST00000682849.1; ENSP00000507965.1; ENSG00000269586.8.
DR GeneID; 102723631; -.
DR KEGG; hsa:102723631; -.
DR MANE-Select; ENST00000682849.1; ENSP00000507965.1; NM_001291529.2; NP_001278458.1.
DR CTD; 102723631; -.
DR GeneCards; CT45A10; -.
DR HGNC; HGNC:51263; CT45A10.
DR HPA; ENSG00000269586; Tissue enriched (testis).
DR neXtProt; NX_P0DMU9; -.
DR OpenTargets; ENSG00000269586; -.
DR VEuPathDB; HostDB:ENSG00000269586; -.
DR eggNOG; KOG3768; Eukaryota.
DR GeneTree; ENSGT00390000016655; -.
DR OMA; CRETVPF; -.
DR OrthoDB; 1187027at2759; -.
DR PhylomeDB; P0DMU9; -.
DR PathwayCommons; P0DMU9; -.
DR SignaLink; P0DMU9; -.
DR BioGRID-ORCS; 102723631; 4 hits in 96 CRISPR screens.
DR GenomeRNAi; 102723631; -.
DR Pharos; P0DMU9; Tdark.
DR PRO; PR:P0DMU9; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; P0DMU9; protein.
DR Bgee; ENSG00000269586; Expressed in right testis and 46 other tissues.
DR GO; GO:0032039; C:integrator complex; IBA:GO_Central.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0034472; P:snRNA 3'-end processing; IBA:GO_Central.
DR InterPro; IPR029307; INT_SG_DDX_CT_C.
DR Pfam; PF15300; INT_SG_DDX_CT_C; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..189
FT /note="Cancer/testis antigen family 45 member A10"
FT /id="PRO_0000433032"
SQ SEQUENCE 189 AA; 21145 MW; 0C4B366EE7BB9E49 CRC64;
MTDKTEKVAV DPETVFKRPR ECDSPSYQKR QRMALLARKQ GAGDSLIAGS AMSKEKKLMT
GHAIPPSQLD SQIDDFTGFS KDGMMQKPGS NAPVGGNVTS NFSGDDLECR GIASSPKSQQ
EINADIKCQV VKEIRCLGRK YEKIFEMLEG VQGPTAVRKR FFESIIKEAA RCMRRDFVKH
LKKKLKRMI
