ID   CT52_CONMI              Reviewed;          62 AA.
AC   Q6PTD0;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Conotoxin Mi5.2 {ECO:0000305};
DE   AltName: Full=Conotoxin Mi T-1 {ECO:0000312|EMBL:AAS93429.1};
DE   Flags: Precursor;
OS   Conus miles (Soldier cone) (Mile cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Rhizoconus.
OX   NCBI_TaxID=69564;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RA   Wang Q., Jiang H., Han Y.H., Chen J.S., Chi C.W.;
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct. {ECO:0000305|Ref.1}.
CC   -!- DOMAIN: The cysteine framework is V (CC-CC). {ECO:0000305}.
CC   -!- PTM: Contains 2 disulfide bonds that can be either 'C1-C3, C2-C4' or
CC       'C1-C4, C2-C3', since these disulfide connectivities have been observed
CC       for conotoxins with cysteine framework V (for examples, see AC P0DQQ7
CC       and AC P81755). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the conotoxin T superfamily. {ECO:0000305}.
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DR   EMBL; AY580326; AAS93429.1; -; mRNA.
DR   AlphaFoldDB; Q6PTD0; -.
DR   ConoServer; 854; Mi5.2 precursor.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR031565; T-conotoxin.
DR   Pfam; PF16981; Chi-conotoxin; 1.
PE   3: Inferred from homology;
KW   Cleavage on pair of basic residues; Disulfide bond; Secreted; Signal;
KW   Toxin.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   PROPEP          20..50
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000274071"
FT   PEPTIDE         52..60
FT                   /note="Conotoxin Mi5.2"
FT                   /id="PRO_0000274072"
SQ   SEQUENCE   62 AA;  6923 MW;  62D5CCFEA47AAFC2 CRC64;
     MRCVPVFIIL LLLIPSASSV DVQPLTRDDV PLASFLDDAR RTLRSPWMTR RCCPGNFACC
     GK