3098B_MYCTU
ID 3098B_MYCTU Reviewed; 66 AA.
AC V5QPS4;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 19-FEB-2014, sequence version 1.
DT 25-MAY-2022, entry version 29.
DE RecName: Full=Putative antitoxin Rv3098B/RVBD_3098B {ECO:0000305};
GN OrderedLocusNames=Rv3098B {ECO:0000305},
GN RVBD_3098B {ECO:0000312|EMBL:AHB18618.1},
GN LH57_16910 {ECO:0000312|EMBL:AIR15879.1};
GN ORFNames=P425_03228 {ECO:0000312|EMBL:KBJ29143.1};
OS Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv).
OC Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium tuberculosis complex.
OX NCBI_TaxID=83332;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RX PubMed=9634230; DOI=10.1038/31159;
RA Cole S.T., Brosch R., Parkhill J., Garnier T., Churcher C.M., Harris D.E.,
RA Gordon S.V., Eiglmeier K., Gas S., Barry C.E. III, Tekaia F., Badcock K.,
RA Basham D., Brown D., Chillingworth T., Connor R., Davies R.M., Devlin K.,
RA Feltwell T., Gentles S., Hamlin N., Holroyd S., Hornsby T., Jagels K.,
RA Krogh A., McLean J., Moule S., Murphy L.D., Oliver S., Osborne J.,
RA Quail M.A., Rajandream M.A., Rogers J., Rutter S., Seeger K., Skelton S.,
RA Squares S., Squares R., Sulston J.E., Taylor K., Whitehead S.,
RA Barrell B.G.;
RT "Deciphering the biology of Mycobacterium tuberculosis from the complete
RT genome sequence.";
RL Nature 393:537-544(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RG The Broad Institute Genome Sequencing Platform;
RA Galagan J., Kreiswirth B., Dobos K., Fortune S., Fitzgerald M., Young S.K.,
RA Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Berlin A.M., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Gnerre S., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Larimer J., McCowan C., Murphy C., Pearson M.,
RA Poon T., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The genome sequence of Mycobacterium tuberculosis H37Rv.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 25618 / H37Rv;
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Earl A.M., Kreiswirth B., Gomez J., Victor T., Desjardins C., Abeel T.,
RA Young S., Zeng Q., Gargeya S., Abouelleil A., Alvarado L., Chapman S.B.,
RA Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M., Howarth C.,
RA Imamovic A., Larimer J., Murphy C., Naylor J., Pearson M., Poon T.W.,
RA Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The genome sequence of Mycobacterium tuberculosis H37Rv.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27294 / TMC 102 / H37Rv;
RA Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J.,
RA Monaco A., King S., Sohrabi A.;
RT "Phylogenetic analysis of Mycobacterial species using whole genome
RT sequences.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative antitoxin component of a possible type II toxin-
CC antitoxin (TA) system. May neutralize the effect of cognate toxin
CC Rv3098A/RVBD_3098A. {ECO:0000305}.
CC -!- SUBUNIT: Forms a complex with cognate toxin Rv3098A/RVBD_3098A.
CC {ECO:0000250|UniProtKB:O53451}.
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DR EMBL; AL123456; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP003248; AHB18618.1; -; Genomic_DNA.
DR EMBL; JLDD01000038; KBJ29143.1; -; Genomic_DNA.
DR EMBL; CP009480; AIR15879.1; -; Genomic_DNA.
DR AlphaFoldDB; V5QPS4; -.
DR SMR; V5QPS4; -.
DR KEGG; mtv:RVBD_3098B; -.
DR PATRIC; fig|83332.111.peg.3451; -.
DR HOGENOM; CLU_189042_0_0_11; -.
DR Proteomes; UP000001584; Chromosome.
PE 3: Inferred from homology;
KW Reference proteome; Toxin-antitoxin system.
FT CHAIN 1..66
FT /note="Putative antitoxin Rv3098B/RVBD_3098B"
FT /id="PRO_0000431256"
SQ SEQUENCE 66 AA; 7701 MW; CD20ABFF54A45DE5 CRC64;
MTATIGFRPT EKDEQIINAA MRSGERKSDV IRRALQLLER EVWIKQARTD AERLRDEDVS
TEPDAW