ID   CT5E_CONTE              Reviewed;          15 AA.
AC   P0DPL7;
DT   12-SEP-2018, integrated into UniProtKB/Swiss-Prot.
DT   12-SEP-2018, sequence version 1.
DT   29-SEP-2021, entry version 6.
DE   RecName: Full=Conotoxin tx5e {ECO:0000305};
DE   AltName: Full=Tx5.5 {ECO:0000305};
OS   Conus textile (Cloth-of-gold cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Cylinder.
OX   NCBI_TaxID=6494;
RN   [1]
RP   PROTEIN SEQUENCE, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR
RP   LOCATION, AND AMIDATION AT THR-15.
RC   TISSUE=Venom;
RX   PubMed=22709442; DOI=10.1021/pr300312h;
RA   Bhatia S., Kil Y.J., Ueberheide B., Chait B.T., Tayo L., Cruz L., Lu B.,
RA   Yates J.R. III, Bern M.;
RT   "Constrained de novo sequencing of conotoxins.";
RL   J. Proteome Res. 11:4191-4200(2012).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:22709442}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC       {ECO:0000305|PubMed:22709442}.
CC   -!- DOMAIN: The cysteine framework is V (CC-CC). {ECO:0000305}.
CC   -!- PTM: Contains 2 disulfide bonds that can be either 'C1-C3, C2-C4' or
CC       'C1-C4, C2-C3', since these disulfide connectivities have been observed
CC       for conotoxins with cysteine framework V (for examples, see AC P0DQQ7
CC       and AC P81755). {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the conotoxin T superfamily. {ECO:0000305}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Disulfide bond; Secreted; Toxin.
FT   PEPTIDE         1..15
FT                   /note="Conotoxin tx5e"
FT                   /evidence="ECO:0000269|PubMed:22709442"
FT                   /id="PRO_0000445053"
FT   MOD_RES         15
FT                   /note="Threonine amide"
FT                   /evidence="ECO:0000269|PubMed:22709442"
FT   UNSURE          2
FT                   /note="I or L"
FT                   /evidence="ECO:0000305|PubMed:22709442"
FT   UNSURE          4
FT                   /note="I or L"
FT                   /evidence="ECO:0000305|PubMed:22709442"
FT   UNSURE          5
FT                   /note="I or L"
FT                   /evidence="ECO:0000305|PubMed:22709442"
SQ   SEQUENCE   15 AA;  1705 MW;  54736BC44E7ED015 CRC64;
     NIQIICCKHT PKCCT