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CTF1_SCHPO
ID   CTF1_SCHPO              Reviewed;         363 AA.
AC   O43040;
DT   14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1998, sequence version 1.
DT   03-AUG-2022, entry version 142.
DE   RecName: Full=Cleavage and termination factor 1;
DE   AltName: Full=Transcription termination factor ctf1;
GN   Name=ctf1; ORFNames=SPBC3B9.11c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   CHARACTERIZATION.
RX   PubMed=11389847; DOI=10.1016/s1097-2765(01)00235-0;
RA   Aranda A., Proudfoot N.;
RT   "Transcriptional termination factors for RNA polymerase II in yeast.";
RL   Mol. Cell 7:1003-1011(2001).
CC   -!- FUNCTION: Component of the cleavage factor I (CF I) involved in pre-
CC       mRNA 3'-end processing.
CC   -!- SUBUNIT: Interacts with res2.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; CU329671; CAA17791.1; -; Genomic_DNA.
DR   PIR; T40350; T40350.
DR   RefSeq; NP_596669.1; NM_001022591.2.
DR   AlphaFoldDB; O43040; -.
DR   SMR; O43040; -.
DR   BioGRID; 277533; 14.
DR   STRING; 4896.SPBC3B9.11c.1; -.
DR   iPTMnet; O43040; -.
DR   SwissPalm; O43040; -.
DR   MaxQB; O43040; -.
DR   PaxDb; O43040; -.
DR   PRIDE; O43040; -.
DR   EnsemblFungi; SPBC3B9.11c.1; SPBC3B9.11c.1:pep; SPBC3B9.11c.
DR   GeneID; 2541018; -.
DR   KEGG; spo:SPBC3B9.11c; -.
DR   PomBase; SPBC3B9.11c; ctf1.
DR   VEuPathDB; FungiDB:SPBC3B9.11c; -.
DR   eggNOG; KOG0108; Eukaryota.
DR   HOGENOM; CLU_028601_0_0_1; -.
DR   InParanoid; O43040; -.
DR   OMA; TKFRLMI; -.
DR   PhylomeDB; O43040; -.
DR   PRO; PR:O43040; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0033620; C:Mei2 nuclear dot complex; IDA:PomBase.
DR   GO; GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; IDA:PomBase.
DR   GO; GO:0005634; C:nucleus; IDA:PomBase.
DR   GO; GO:0003729; F:mRNA binding; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; ISM:PomBase.
DR   GO; GO:0007129; P:homologous chromosome pairing at meiosis; EXP:PomBase.
DR   GO; GO:0031124; P:mRNA 3'-end processing; IPI:PomBase.
DR   GO; GO:0006378; P:mRNA polyadenylation; IC:PomBase.
DR   GO; GO:0098789; P:pre-mRNA cleavage required for polyadenylation; IBA:GO_Central.
DR   Gene3D; 1.10.20.70; -; 1.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR025742; CSTF2_hinge.
DR   InterPro; IPR026896; CSTF_C.
DR   InterPro; IPR038192; CSTF_C_sf.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF14327; CSTF2_hinge; 1.
DR   Pfam; PF14304; CSTF_C; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   1: Evidence at protein level;
KW   mRNA processing; Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..363
FT                   /note="Cleavage and termination factor 1"
FT                   /id="PRO_0000081537"
FT   DOMAIN          7..85
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          291..325
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        291..322
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   363 AA;  39963 MW;  66177BD3664E110C CRC64;
     MSMTAGNVVF VGNIPYDVSE QQMTEIFNQV GPVKTFKLVL DPETGSGKGY GFCEFFDSET
     TAMAVRKLNN SELGPRKIRV EFPSNDPRRN QSYEYTERTD RYMEQQNAHE SSYNSRFIPP
     VLHSTSSLPA SQGGGMPSPA IYSSSMATNL NKNINSTSVP AYNFHNSMTS DFDSASQPHT
     DAYNARTFQY NKSSQNKGDY TSGTSISNPT SIPLAPSVVQ VLSTFSAQEL LNMLSKLQTV
     VHIAPEEARR LLIANPALPY AAFQAMLLMN LVDANVLQQV VVAVKNKNMH QPASATSSPP
     SVPQKIPSSN HKSQQANGSD QGNEGKRMAL IQQLLALTPE QINALPPAQR DQILSIRRQH
     FRQ
 
 
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