CTGE3_HUMAN
ID CTGE3_HUMAN Reviewed; 158 AA.
AC Q8IX95;
DT 04-JAN-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Putative cTAGE family member 3;
DE Short=Protein cTAGE-3;
GN Name=CTAGE3P; Synonyms=CTAGE3;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RC TISSUE=Testis;
RX PubMed=12839582; DOI=10.1046/j.1523-1747.2003.12318.x;
RA Usener D., Schadendorf D., Koch J., Duebel S., Eichmueller S.;
RT "cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-
RT specific splicing.";
RL J. Invest. Dermatol. 121:198-206(2003).
CC -!- FUNCTION: Tumor-associated antigen.
CC -!- TISSUE SPECIFICITY: Expressed in normal tissues including colon,
CC mammary gland, ovary, placenta, stomach and testis, as well as several
CC fetal tissues. {ECO:0000269|PubMed:12839582}.
CC -!- MISCELLANEOUS: Tumor-associated antigen found in several cutaneous T-
CC cell lymphoma (CTCL). Expressed in 4 of 11 Mycosis fungoides tissues
CC and in a T-zone lymphoma.
CC -!- SIMILARITY: Belongs to the cTAGE family. {ECO:0000305}.
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR EMBL; AF338231; AAN77608.1; -; mRNA.
DR AlphaFoldDB; Q8IX95; -.
DR SMR; Q8IX95; -.
DR BioMuta; HGNC:24348; -.
DR EPD; Q8IX95; -.
DR jPOST; Q8IX95; -.
DR MassIVE; Q8IX95; -.
DR MaxQB; Q8IX95; -.
DR PeptideAtlas; Q8IX95; -.
DR PRIDE; Q8IX95; -.
DR ProteomicsDB; 70977; -.
DR GeneCards; CTAGE3P; -.
DR HGNC; HGNC:24348; CTAGE3P.
DR MIM; 608857; gene.
DR neXtProt; NX_Q8IX95; -.
DR InParanoid; Q8IX95; -.
DR ChiTaRS; CTAGE3P; human.
DR Pharos; Q8IX95; Tdark.
DR PRO; PR:Q8IX95; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q8IX95; protein.
DR GO; GO:0070971; C:endoplasmic reticulum exit site; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR GO; GO:0035459; P:vesicle cargo loading; IBA:GO_Central.
PE 5: Uncertain;
KW Coiled coil; Reference proteome.
FT CHAIN 1..158
FT /note="Putative cTAGE family member 3"
FT /id="PRO_0000189539"
FT COILED 26..96
FT /evidence="ECO:0000255"
SQ SEQUENCE 158 AA; 18015 MW; 899FC9B146098E7D CRC64;
MTFKGFQMNE EKLEIGIQDA SSENCQLQES QKQLLQEAEV WKEQVSELNK QKITFEDSKV
HAEQVLNDKE NHIETLTERL LKIKDQAAVL EEDITDDGNL ELEMNSELKD GAYLDNPPKG
ALKKLIHAAK LNASLTTLEG ERNQFIFSYL KLIKPGRA