ID   CTL1L_CAEBR             Reviewed;         788 AA.
AC   A8XKF2;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Choline transporter-like protein 1;
GN   Name=chtl-1; ORFNames=CBG14673;
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTL (choline transporter-like) family.
CC       {ECO:0000305}.
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DR   EMBL; HE600983; CAP33126.2; -; Genomic_DNA.
DR   AlphaFoldDB; A8XKF2; -.
DR   SMR; A8XKF2; -.
DR   STRING; 6238.CBG14673; -.
DR   WormBase; CBG14673a; CBP03601; WBGene00035096; Cbr-chtl-1.
DR   eggNOG; KOG1362; Eukaryota.
DR   HOGENOM; CLU_017181_3_1_1; -.
DR   InParanoid; A8XKF2; -.
DR   OMA; CIAYWAC; -.
DR   OrthoDB; 329225at2759; -.
DR   Proteomes; UP000008549; Chromosome X.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR007603; Choline_transptr-like.
DR   PANTHER; PTHR12385; PTHR12385; 1.
DR   Pfam; PF04515; Choline_transpo; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..788
FT                   /note="Choline transporter-like protein 1"
FT                   /id="PRO_0000359728"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        329..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        352..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        409..429
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        458..478
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        531..551
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        583..603
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        620..640
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        679..699
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        718..738
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        276
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        497
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   788 AA;  89635 MW;  9093B78A91420C06 CRC64;
     MARKKRTMPA AEVYEKSDSF GQLPSAPPIS PHRMDHIYPD SYGSPPPLHQ AYHVQPARAN
     YVPDQIARFN VIKPDRLAKR HNPQLYTKRG CTDVFCCFLF FVFLCGWVVV ASLGIMWGDP
     QRLIYPTDSE FRRCGVDQGG YYNFRYLQFF QIFTNKDIFS KRPYLFYFDL TKCISYATAL
     GGCQTTQICV EECPSQYFSY LQLRTASAAE IQNKMKNVVY CTDDVDKSTV TTFVALQSLV
     QRGKCVSYTV KSVPVLQRCF PEAIFNAVDN VNTVLNSSNS LDYLKRTFGD DALIPQDIQI
     TGQSSEVMKS VVEDQPVTHK VIHDLSQTWW QTLILIFAAG MLSFIWTVIM RLLGSLLIWL
     SIFLVLGALG FGAGFSWIKW NNLKATGAID DYSFHPAFDA YFEMPTTWFV VAIATSVLLV
     IFLLVILFIR QRISIACALI SESSKAIGSM MSTLVFPLFP FLLHIGVFAL WGSIAIWLAS
     SGQEICRMKE TNGQVYNTST KCDCNAKLAG CTYVGIEKES DTIFWLQVYN LFAFFWLSCF
     VTALGDIALA GAFASYYWAR DKRHDVPTFP VIRALNRAMR YNLGSIAFGS LIIAIVKIIR
     VMLEYIDHKL GKSENKAVKW FLMCLKCCFW CLEMFFKFLT KNAYIMIAIY GKNFFSSAKD
     SFLLITRNIV RTVVVHKVAG ILLFLGKAMI TLGMGILSFY YFSGRWVVEG VPKVDLYYYF
     VPIVIVVIGS YFMADLFFDV YEMAVDTTFI CFLEDSEQND GSLERPYFMS QKLLEILGTK
     NEIPLHTK