ID   CTL2A_DANRE             Reviewed;         469 AA.
AC   Q08BB5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=CTD small phosphatase-like protein 2-A;
DE            Short=CTDSP-like 2-A;
DE            EC=3.1.3.-;
GN   Name=ctdspl2a; ORFNames=zgc:154017;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable phosphatase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTDSPL2 family. {ECO:0000305}.
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DR   EMBL; BC124794; AAI24795.1; -; mRNA.
DR   RefSeq; NP_001071012.1; NM_001077544.1.
DR   AlphaFoldDB; Q08BB5; -.
DR   SMR; Q08BB5; -.
DR   STRING; 7955.ENSDARP00000082411; -.
DR   PaxDb; Q08BB5; -.
DR   PRIDE; Q08BB5; -.
DR   Ensembl; ENSDART00000087978; ENSDARP00000082411; ENSDARG00000061587.
DR   GeneID; 558181; -.
DR   KEGG; dre:558181; -.
DR   CTD; 558181; -.
DR   ZFIN; ZDB-GENE-061013-647; ctdspl2a.
DR   eggNOG; KOG1605; Eukaryota.
DR   GeneTree; ENSGT01040000240503; -.
DR   HOGENOM; CLU_034042_4_0_1; -.
DR   InParanoid; Q08BB5; -.
DR   OMA; PKKQLVX; -.
DR   OrthoDB; 1176152at2759; -.
DR   PhylomeDB; Q08BB5; -.
DR   TreeFam; TF354278; -.
DR   PRO; PR:Q08BB5; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 25.
DR   Bgee; ENSDARG00000061587; Expressed in early embryo and 26 other tissues.
DR   ExpressionAtlas; Q08BB5; baseline.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR011948; Dullard_phosphatase.
DR   InterPro; IPR004274; FCP1_dom.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   Pfam; PF03031; NIF; 1.
DR   SMART; SM00577; CPDc; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR   PROSITE; PS50969; FCP1; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..469
FT                   /note="CTD small phosphatase-like protein 2-A"
FT                   /id="PRO_0000331468"
FT   DOMAIN          286..445
FT                   /note="FCP1 homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00336"
FT   REGION          1..42
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          73..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          181..209
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          231..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        22..42
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..95
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        182..197
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   469 AA;  52989 MW;  119B3623FC5C1FE8 CRC64;
     MRLRVRKASQ QRSATPSART VKTKRKHSEV EHSLSTEDAK MQKRDTGIFS TIKRFIRGNA
     VKVEQCTPAK RSRVDCDSDS NLITSTPTGG NLPSRANPKT RRKGPVNGDT MTGQNKPVKP
     NGKLEVQAET PSSPPRTTLL GTIFSPVFSF FSPANKNATA GSDSPGQAVE AEEIVKQLDM
     EQLEETPTST TTDGRDLTFD PALNPRPLPH IDTTVEEGEI VTEADMPPLT AVGSNSNYPD
     VPPSPPAEGT YEEDWEVFDP YFFIKHVPPL TEEQLTRKPA LPLKTRSTPE FSLVLDLDET
     LVHCSLNELE DAALTFPVLF QDVIYQVYVR LRPFFREFLE RMSQIYEIIL FTASKKVYAD
     KLLNILDPKK QLVRHRLFRE HCVCVQGNYI KDLNILGRDL SKTVIIDNSP QAFAYQLSNG
     IPIESWFVDK NDNELLKLVP FLEKLVELNE DVRPYIRERF RLHDLLPPD