ID   CTL2A_XENLA             Reviewed;         466 AA.
AC   Q801R4; Q0IH06;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=CTD small phosphatase-like protein 2-A;
DE            Short=CTDSP-like 2-A;
DE            EC=3.1.3.-;
GN   Name=ctdspl2-a; Synonyms=ctdspl2a;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, Oocyte, and Thymus;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable phosphatase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTDSPL2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI23380.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC047962; AAH47962.1; -; mRNA.
DR   EMBL; BC123379; AAI23380.1; ALT_INIT; mRNA.
DR   EMBL; BC129524; AAI29525.1; -; mRNA.
DR   RefSeq; NP_001080602.1; NM_001087133.1.
DR   AlphaFoldDB; Q801R4; -.
DR   SMR; Q801R4; -.
DR   DNASU; 380294; -.
DR   GeneID; 380294; -.
DR   KEGG; xla:380294; -.
DR   CTD; 380294; -.
DR   Xenbase; XB-GENE-6253913; ctdspl2.S.
DR   OMA; PKKQLVX; -.
DR   OrthoDB; 1176152at2759; -.
DR   Proteomes; UP000186698; Chromosome 3S.
DR   Bgee; 380294; Expressed in blastula and 19 other tissues.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR011948; Dullard_phosphatase.
DR   InterPro; IPR004274; FCP1_dom.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   Pfam; PF03031; NIF; 1.
DR   SMART; SM00577; CPDc; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR   PROSITE; PS50969; FCP1; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..466
FT                   /note="CTD small phosphatase-like protein 2-A"
FT                   /id="PRO_0000331470"
FT   DOMAIN          283..442
FT                   /note="FCP1 homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00336"
FT   REGION          1..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          189..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        189..203
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   466 AA;  52960 MW;  0968F0A618DF3437 CRC64;
     MRLRMRKGSP RSSHVAAVRT ARCKRKHSEE DEEEESPLIE EDKLPKQETG LLSTIKNFIK
     GSTNKEDREN PAKRSKVERD LDNNLITSTP RTGDKPSKPI ARVRRKSQVN GEATAYEVSQ
     HMKQNGKLED LPCTTSPPRT TLLGTIFSPV FNFFSPANKN GTSGSDSPGQ AVEAEEIVKQ
     LDMEKVDEFS TSTATNGASY PSLGAPVRST AGSWLEGTED TPERDIPPLT APVSPESGYS
     SAHAEAAYEE DWEVFDPYFF IKHVPPLTEE QLNRKPALPL KTRSTPEFSL VLDLDETLVH
     CSLNELEDAA LTFPVLFQDV IYQVYVRLRP FFREFLERMS QIYEIILFTA SKKVYADKLL
     NILDPKKRLV RHRLFREHCV CVQGNYIKDL NILGRDLSKT IIIDNSPQAF AYQLSNGIPI
     ESWFMDKNDK ELLKLVPFLE NLVELNEDVR PHVRDRFRLH DCLPPD