ID   CTL2B_XENLA             Reviewed;         466 AA.
AC   Q3KQB6; Q2TAQ9;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=CTD small phosphatase-like protein 2-B;
DE            Short=CTDSP-like 2-B;
DE            EC=3.1.3.-;
GN   Name=ctdspl2-b; Synonyms=ctdspl2b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable phosphatase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTDSPL2 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC106290; AAI06291.1; -; mRNA.
DR   EMBL; BC110766; AAI10767.1; -; mRNA.
DR   RefSeq; NP_001089935.1; NM_001096466.1.
DR   RefSeq; XP_018106755.1; XM_018251266.1.
DR   AlphaFoldDB; Q3KQB6; -.
DR   SMR; Q3KQB6; -.
DR   DNASU; 735004; -.
DR   GeneID; 735004; -.
DR   KEGG; xla:735004; -.
DR   CTD; 735004; -.
DR   Xenbase; XB-GENE-950107; ctdspl2.L.
DR   OrthoDB; 1176152at2759; -.
DR   Proteomes; UP000186698; Chromosome 3L.
DR   Bgee; 735004; Expressed in blastula and 19 other tissues.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR011948; Dullard_phosphatase.
DR   InterPro; IPR004274; FCP1_dom.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   Pfam; PF03031; NIF; 1.
DR   SMART; SM00577; CPDc; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR   PROSITE; PS50969; FCP1; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..466
FT                   /note="CTD small phosphatase-like protein 2-B"
FT                   /id="PRO_0000331471"
FT   DOMAIN          283..442
FT                   /note="FCP1 homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00336"
FT   REGION          1..111
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          192..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        192..217
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        205
FT                   /note="A -> S (in Ref. 1; AAI10767)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   466 AA;  52949 MW;  CECD06167D2E8DFE CRC64;
     MRLRTRKGSP RSSHGAAGRT ARCKRKHSEE DEEEESPLIE EDKLPTQETG LLSTIKNFIK
     GSTNKEDREN PAKKSRVERD FDNNLITSTP RTGDKPSKPI ARVRRKSQVN GEATAYEVSQ
     HMKQNGKLED LPCTTSPPRT TLLGTIFSPV FNFFSPANKN GTSGSDSPGQ AVEAEEIVKQ
     LDMEKVDEFS TNTATNGASY PSPGAPVRTT ASSWLEGTED TPEREIPPLT APVSPESGYS
     SAHAEAAYEE DWEVFDPYFF IKHVPPLTEE QLNRKPALPL KTRSTPEFSL VLDLDETLVH
     CSLNELEDAA LTFPVLFQDV IYQVYVRLRP FFREFLERMS QIYEIILFTA SKKVYADKLL
     NILDPKKRLV RHRLFREHCV CVQGNYIKDL NILGRDLSKT IIIDNSPQAF AYQLSNGIPI
     ESWFMDKNDK ELLKLVPFLQ KLVELNEDVR PHIRDRFRLH DCLPPD