ID   CTL3_BOVIN              Reviewed;         649 AA.
AC   A5PK40;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Choline transporter-like protein 3;
DE   AltName: Full=Solute carrier family 44 member 3;
GN   Name=SLC44A3; Synonyms=CTL3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal pons;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUN-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTL (choline transporter-like) family.
CC       {ECO:0000305}.
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DR   EMBL; BC142344; AAI42345.1; -; mRNA.
DR   RefSeq; NP_001092370.1; NM_001098900.2.
DR   AlphaFoldDB; A5PK40; -.
DR   STRING; 9913.ENSBTAP00000033454; -.
DR   PaxDb; A5PK40; -.
DR   Ensembl; ENSBTAT00000075458; ENSBTAP00000063549; ENSBTAG00000020344.
DR   GeneID; 507455; -.
DR   KEGG; bta:507455; -.
DR   CTD; 126969; -.
DR   VEuPathDB; HostDB:ENSBTAG00000020344; -.
DR   VGNC; VGNC:34877; SLC44A3.
DR   eggNOG; KOG1362; Eukaryota.
DR   GeneTree; ENSGT00940000160336; -.
DR   HOGENOM; CLU_017181_2_0_1; -.
DR   InParanoid; A5PK40; -.
DR   OMA; QCLGAEY; -.
DR   OrthoDB; 329225at2759; -.
DR   TreeFam; TF313325; -.
DR   Proteomes; UP000009136; Chromosome 3.
DR   Bgee; ENSBTAG00000020344; Expressed in prostate gland and 96 other tissues.
DR   ExpressionAtlas; A5PK40; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0015101; F:organic cation transmembrane transporter activity; IEA:UniProt.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0071705; P:nitrogen compound transport; IEA:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR007603; Choline_transptr-like.
DR   PANTHER; PTHR12385; PTHR12385; 1.
DR   Pfam; PF04515; Choline_transpo; 1.
PE   2: Evidence at transcript level;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..649
FT                   /note="Choline transporter-like protein 3"
FT                   /id="PRO_0000359719"
FT   TRANSMEM        33..53
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        213..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        235..255
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        284..304
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        384..404
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        533..553
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        562..582
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        136
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        151
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        414
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        502
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        520
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   649 AA;  73220 MW;  1D95F582B4A0C9DE CRC64;
     MQCLGAEHLD SAERIPTQRQ WRPQIYRKCT DTAWLFLFFL FWTGLVFIMG YSVAAGATGR
     LLFGYDSFGN VCGKKNSPVE GAPLSGQDMT QKKHVFFMNS CNLEVKDVRL SSTVLCVSSC
     PEEQLDTLEE VQLFANTSGS FLCVYNLNSF NYTQIPNADL LCPRLPVPPS KSFPLFNRCI
     PQTPECYSLF ASVLINDVDS LHRILSGIMS GRDTVLGLCI LAFALSLAMM FTFRFITTLL
     VHIFIALIVL GLLFVCSVLW WLYYDYTNDL SIELDTEREN MKCLLGFAIV STVITAVLLI
     LIYVLRKRIK LTVELLQVTN KAISSSPFLL FQPLWTFAIL IFFWVLWVAV LLSLGTAGAA
     QVVEGGQVEY KPLSGIRYMW WYHLIGLIWT SEFILACQQM AVAGTVVTCY FNRNKSDPPD
     RPILSSLSIL FCYHQGTVVK GSFLITVVRI PRAVLMYVYN TLKEKDGALS RCVSQCCCCC
     FWCLDKCLRH LNQNAYTTTA INGTDFCTSA KDALKLLSKN SSHFTSVNCF GDFIIFLGKV
     LVVCFTVFGG LMAFNYHRVL QVWAVPLLLV AFFAYLVAHS FLSVFETVLD ALFLCFAVDL
     ETNDGSSEKP YFMDQEFLNF VKRINKLNTR AQRNKNSLTS EEGTELRPL