ID   CTLHC_DICDI             Reviewed;         506 AA.
AC   Q55CN8;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=CTL-like protein DDB_G0269978;
GN   ORFNames=DDB_G0269978;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000250}; Multi-pass membrane
CC       protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTL (choline transporter-like) family.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000005; EAL72339.1; -; Genomic_DNA.
DR   RefSeq; XP_646443.1; XM_641351.1.
DR   AlphaFoldDB; Q55CN8; -.
DR   STRING; 44689.DDB0190711; -.
DR   PaxDb; Q55CN8; -.
DR   EnsemblProtists; EAL72339; EAL72339; DDB_G0269978.
DR   GeneID; 8617402; -.
DR   KEGG; ddi:DDB_G0269978; -.
DR   dictyBase; DDB_G0269978; -.
DR   eggNOG; KOG1362; Eukaryota.
DR   HOGENOM; CLU_539099_0_0_1; -.
DR   InParanoid; Q55CN8; -.
DR   OMA; ITPISEC; -.
DR   PhylomeDB; Q55CN8; -.
DR   PRO; PR:Q55CN8; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016020; C:membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   InterPro; IPR007603; Choline_transptr-like.
DR   PANTHER; PTHR12385; PTHR12385; 1.
DR   Pfam; PF04515; Choline_transpo; 1.
PE   3: Inferred from homology;
KW   Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..506
FT                   /note="CTL-like protein DDB_G0269978"
FT                   /id="PRO_0000359737"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        161..181
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        182..202
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        226..246
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        256..276
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        279..299
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        345..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        371..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        416..436
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        447..467
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        15
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        41
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   506 AA;  58008 MW;  FD2398006CA8BFA8 CRC64;
     MGINDNGIYG SLKGNSTTGG IYKMGDHNTG YGEKNNQNNN NKSGGKTIVN GVIVNSNQQK
     LKGDENEFDH SQDDNADEFN KFPKKVKYND LLYSVLFAIQ MVLFITMTVI AGTKHPNKKE
     FVEYSLQGLL IIAISIPLIL AFFLIWKKIF KIHPTNMIKT SFFSLMITGI LFIGLLIGNG
     WYSWAIVFGI TLISLIFFYF AFRDKIPFVG IIISLVLKII EKYPSTLLVS FVCLIISCVY
     YNIWLFSVSY NFYYDSYWTA WSYMKFMFLV FNLYWTHYVI TYTCYSVVSG LVASWYFFAD
     EDFNGMPPKP CAHSLYRSMT SSFGSIAFGS LLVCLVQMVQ FICRGFARVP GLTSLFCNCL
     QFIALIFTRM LYTFNIYTFS MVSIYGQSFC NSSKKTYNLM VNNNEKLFAT HNYMLITMLS
     VSLSMFLIIG FIVTMIMATI QLENQGWLYV QLVMFLFILY KPFDIIFSSV LTILMCLISD
     PNAMEVTKPN TFILLSETYD FKSLNP