ID   CTNC_DICDI              Reviewed;         222 AA.
AC   Q86HV8; Q551J9;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Countin-3;
DE   Flags: Precursor;
GN   Name=ctnC; ORFNames=DDB_G0276479;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND DEVELOPMENTAL STAGE.
RX   PubMed=12385972; DOI=10.1080/1025814021000014001;
RA   Okuwa T., Katayama T., Takano A., Yasukawa H.;
RT   "Identification of the homolog of cell-counting factor in the cellular
RT   slime mold Dictyostelium discoideum.";
RL   J. Biochem. Mol. Biol. Biophys. 6:351-355(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: May control the size of the multicellular structure.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- DEVELOPMENTAL STAGE: Expressed in the vegetative cells, decreases in
CC       the aggregating stage, increases in the mid-developmental stage and
CC       decreases again in subsequent stages. {ECO:0000269|PubMed:12385972}.
CC   -!- SIMILARITY: Belongs to the countin family. {ECO:0000305}.
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DR   EMBL; AB211530; BAD98303.1; -; Genomic_DNA.
DR   EMBL; AAFI02000015; EAL69193.1; -; Genomic_DNA.
DR   RefSeq; XP_643135.1; XM_638043.1.
DR   AlphaFoldDB; Q86HV8; -.
DR   PaxDb; Q86HV8; -.
DR   EnsemblProtists; EAL69193; EAL69193; DDB_G0276479.
DR   GeneID; 8620541; -.
DR   KEGG; ddi:DDB_G0276479; -.
DR   dictyBase; DDB_G0276479; ctnC.
DR   eggNOG; ENOG502S5J5; Eukaryota.
DR   HOGENOM; CLU_095805_0_0_1; -.
DR   InParanoid; Q86HV8; -.
DR   OMA; ICEEWIP; -.
DR   PhylomeDB; Q86HV8; -.
DR   PRO; PR:Q86HV8; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR008139; SaposinB_dom.
DR   SMART; SM00741; SapB; 1.
DR   PROSITE; PS50015; SAP_B; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..222
FT                   /note="Countin-3"
FT                   /id="PRO_0000327910"
FT   DOMAIN          21..105
FT                   /note="Saposin B-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT   CARBOHYD        108
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT   CARBOHYD        134
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT   CARBOHYD        218
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT   DISULFID        25..101
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT   DISULFID        28..95
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
FT   DISULFID        56..68
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00415"
SQ   SEQUENCE   222 AA;  24114 MW;  A35CF4987A7A75DA CRC64;
     MNKILSLFLI TILLISKVMS SSEECKLCTD FMYDSLNELI EIAINGGVIG SCGALCNKLG
     IAPLCMVCAI ACDAVGINGF MDLLQDVFPD PIYICESVKM CQYNDKANAT ITEVVINPMS
     GNVGDTFKIG VSFNVTNTIA TGEILWNVVD PRGFQFGETE VIIDAAPSIY GAAFSFQATP
     SEQEEFPPGE YQLQMQICEG TCGSPHPHSY ILSNQYLNFT II