ID   CTR86_KLULA             Reviewed;         537 AA.
AC   Q6CTY9;
DT   20-MAR-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Copper transport protein 86;
GN   Name=CTR86; OrderedLocusNames=KLLA0C08998g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Essential protein which may be involved in threonine
CC       biosynthesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTR86 family. {ECO:0000305}.
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DR   EMBL; CR382123; CAH01451.1; -; Genomic_DNA.
DR   RefSeq; XP_452600.1; XM_452600.1.
DR   AlphaFoldDB; Q6CTY9; -.
DR   STRING; 28985.XP_452600.1; -.
DR   EnsemblFungi; CAH01451; CAH01451; KLLA0_C08998g.
DR   GeneID; 2892320; -.
DR   KEGG; kla:KLLA0_C08998g; -.
DR   eggNOG; KOG2676; Eukaryota.
DR   HOGENOM; CLU_043683_0_0_1; -.
DR   InParanoid; Q6CTY9; -.
DR   OMA; TNFPECK; -.
DR   Proteomes; UP000000598; Chromosome C.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009088; P:threonine biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019156; Ataxin-10_domain.
DR   Pfam; PF09759; Atx10homo_assoc; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis; Cytoplasm; Reference proteome;
KW   Threonine biosynthesis.
FT   CHAIN           1..537
FT                   /note="Copper transport protein 86"
FT                   /id="PRO_0000280689"
SQ   SEQUENCE   537 AA;  61224 MW;  635579DF92238743 CRC64;
     MSEIRWSKLH SLIHDAPSDS GEYITIIDSL NDLIKETTIE DRRNEIASSK DIFFQLRESA
     ILGKSVDLKQ ACSSQYMRIV KGIVIIARNL SVANQVIPQN ILLPNTFLAW YLSISRQTVC
     TPGDLKQLYG LVCQFYFNCT RTNVVFDESC FDDHMNFMVE MLRFIDDDGI VNAYSLWLSN
     IMKSDAFISS LLNDIRSLEV IDKLLLRGII AQKTEIDLLV EEEDEDKNLS SLATIQLKIL
     KQLVTHECFG SYMKTLRKEY GFASFNKMFK IVTMLVTSSE RWDLYQLTAI LSWTFDIFEE
     YTYLVDAFFK SESTPEATDA GPLFAILSSV LDILTTLAKY QHAQKYMISY DGVHKIIKLF
     DILERNCLKI HFNKSSGAKN VDSSAHPVRA TDHVGNVITD AVILKKRIHN NRINDSNFPG
     IKCFLVELLG FMSYEQKDVQ DSVRELHGLE LVLSNCIIDD NNPFIKERCI ICIRYLLANN
     STNQEFISQL EAKKAVDGDV LKKAGYKVDI DGKGNIKLTA DKRNAASEEQ LFEDVQK