ID   CTRA_NEIME              Reviewed;         391 AA.
AC   P0A0V9; P32013;
DT   15-FEB-2005, integrated into UniProtKB/Swiss-Prot.
DT   15-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Capsule polysaccharide export outer membrane protein CtrA;
DE   Flags: Precursor;
GN   Name=ctrA;
OS   Neisseria meningitidis.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=487;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=C1701, Serogroup Y, and W135;
RX   PubMed=1371768; DOI=10.1128/iai.60.3.798-803.1992;
RA   Frosch M., Mueller D., Bousset K., Mueller A.;
RT   "Conserved outer membrane protein of Neisseria meningitidis involved in
RT   capsule expression.";
RL   Infect. Immun. 60:798-803(1992).
CC   -!- FUNCTION: Involved in transport of capsular polysaccharides to the cell
CC       surface. May function as a membrane anchor for capsular
CC       polysaccharides. Possible porin properties.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the BexD/CtrA/VexA family. {ECO:0000305}.
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DR   EMBL; M57677; AAA25450.1; -; Genomic_DNA.
DR   RefSeq; WP_002215290.1; NZ_WSOH01000064.1.
DR   AlphaFoldDB; P0A0V9; -.
DR   SMR; P0A0V9; -.
DR   GeneID; 61282337; -.
DR   OMA; DRADARN; -.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR   GO; GO:0015159; F:polysaccharide transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   InterPro; IPR003715; Poly_export.
DR   Pfam; PF02563; Poly_export; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Cell outer membrane; Ion transport;
KW   Lipoprotein; Membrane; Palmitate; Polysaccharide transport; Porin; Signal;
KW   Sugar transport; Transmembrane; Transmembrane beta strand; Transport.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           23..391
FT                   /note="Capsule polysaccharide export outer membrane protein
FT                   CtrA"
FT                   /id="PRO_0000025219"
FT   TOPO_DOM        23..33
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..43
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        44..57
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        58..67
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        68..83
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        84..93
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        94..117
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..127
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        128..135
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        136..145
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        146..148
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..158
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        159..161
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        162..171
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        172..178
FT                   /note="Extracellular"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..188
FT                   /note="Beta stranded"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        189..391
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   LIPID           23
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           23
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   391 AA;  41949 MW;  0F9434CF247F9FAD CRC64;
     MFKVKFYIRH AVLLLCGSLI VGCSAIPSSG PSAKKIVSLG QQSEVQIPEV ELIDVNHTVA
     QLLYKAQINQ SFTQFGDGYA SAGTLNIGDV LDIMIWEAPP AVLFGGGLSS MGSGSAHQTK
     LPEQLVTARG TVSVPFVGDI SVVGKTPGQV QEIIKGRLKK MANQPQVMVR LVQNNAANVS
     VIRAGNSVRM PLTAAGERVL DAVAAVGGST ANVQDTNVQL TRGNVVRTVA LEDLVANPRQ
     NILLRRGDVV TMITNPYTFT SMGAVGRTQE IGFSARGLSL SEAIGRMGGL QDRRSDARGV
     FVFRYTPLVE LPAERQDKWI AQGYGSEAEI PTVYRVNMAD AHSLFSMQRF PVKNKDVLYV
     SNAPLAEVQK FLSFVFSPVT SGANSINNLT N