ID   CTRB_NEIMA              Reviewed;         387 AA.
AC   P57034; A1IP52;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Capsule polysaccharide export inner-membrane protein CtrB;
GN   Name=ctrB; OrderedLocusNames=NMA0197;
OS   Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 /
OS   Z2491).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122587;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15465 / Z2491;
RX   PubMed=10761919; DOI=10.1038/35006655;
RA   Parkhill J., Achtman M., James K.D., Bentley S.D., Churcher C.M.,
RA   Klee S.R., Morelli G., Basham D., Brown D., Chillingworth T., Davies R.M.,
RA   Davis P., Devlin K., Feltwell T., Hamlin N., Holroyd S., Jagels K.,
RA   Leather S., Moule S., Mungall K.L., Quail M.A., Rajandream M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Whitehead S., Spratt B.G.,
RA   Barrell B.G.;
RT   "Complete DNA sequence of a serogroup A strain of Neisseria meningitidis
RT   Z2491.";
RL   Nature 404:502-506(2000).
CC   -!- FUNCTION: May form an ATP-driven capsule polysaccharide export
CC       apparatus, in association with the CtrC and CtrD proteins.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BexC/CtrB/KpsE family. {ECO:0000305}.
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DR   EMBL; AL157959; CAM07511.1; -; Genomic_DNA.
DR   PIR; H82013; H82013.
DR   RefSeq; WP_002236581.1; NC_003116.1.
DR   AlphaFoldDB; P57034; -.
DR   SMR; P57034; -.
DR   EnsemblBacteria; CAM07511; CAM07511; NMA0197.
DR   KEGG; nma:NMA0197; -.
DR   HOGENOM; CLU_027864_0_1_4; -.
DR   OMA; LYMAFIA; -.
DR   BioCyc; NMEN122587:NMA_RS01015-MON; -.
DR   Proteomes; UP000000626; Chromosome.
DR   GO; GO:0009276; C:Gram-negative-bacterium-type cell wall; IEA:InterPro.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005351; F:carbohydrate:proton symporter activity; IEA:InterPro.
DR   GO; GO:0015774; P:polysaccharide transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005705; BexC_CtrB_KpsE_VexD.
DR   TIGRFAMs; TIGR01010; BexC_CtrB_KpsE; 1.
PE   3: Inferred from homology;
KW   Capsule biogenesis/degradation; Cell inner membrane; Cell membrane;
KW   Membrane; Polysaccharide transport; Sugar transport; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..387
FT                   /note="Capsule polysaccharide export inner-membrane protein
FT                   CtrB"
FT                   /id="PRO_0000079497"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        358..378
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   387 AA;  43345 MW;  9C6CF879DC9EB6D1 CRC64;
     MSEQLPVAVA TETKAERKKP KKKSWIKKLS PLFWVTVIIP TVISLVYFGF FASDRFTSQS
     SFVVRSPKSQ SSLNGLGAIL QGTGFARAQD DIYTVQEYMQ SRSALDALRK KMPIRDFYEK
     EGDIFSRFNG FGLRGEDEAF YQYYRDKVSI HFDSVSGISN LSVTSFNAGE SQKINDALLK
     QGEVLINQLN ERARQDTIRY AQEVVNSAEE QVKEASVQLT KFRVSNGIFD LKAQSDVQMG
     LVSKLQDELI VIQTQLDQVK AVTPENPQIP GLIAREKSLR KEISQQMKAI SGGGEGSLSN
     QAAEYQRVYL ENELAEKQLA AAMTSLESAK AEADRQQLYL EVISQPNKPD LAYEPNRLYN
     IVATFVIGLI VYGIVVLLSA SIREHKN