ID   CTRP_PENMO              Reviewed;          31 AA.
AC   P35002;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Chymotrypsin;
DE            EC=3.4.21.1;
DE   Flags: Fragment;
OS   Penaeus monodon (Giant tiger prawn).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Dendrobranchiata;
OC   Penaeoidea; Penaeidae; Penaeus.
OX   NCBI_TaxID=6687;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Midgut;
RX   PubMed=1657178; DOI=10.1016/0167-4838(91)90112-d;
RA   Tsai I.H., Lu P.J., Chuang J.L.;
RT   "The midgut chymotrypsins of shrimps (Penaeus monodon, Penaeus japonicus
RT   and Penaeus penicillatus).";
RL   Biochim. Biophys. Acta 1080:59-67(1991).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-
CC         Xaa.; EC=3.4.21.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10078,
CC         ECO:0000255|PROSITE-ProRule:PRU10079};
CC   -!- SUBCELLULAR LOCATION: Secreted, extracellular space.
CC   -!- SIMILARITY: Belongs to the peptidase S1 family. {ECO:0000255|PROSITE-
CC       ProRule:PRU00274}.
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DR   PIR; S18356; S18356.
DR   AlphaFoldDB; P35002; -.
DR   SMR; P35002; -.
DR   MEROPS; S01.122; -.
DR   GO; GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.10.10; -; 1.
DR   InterPro; IPR009003; Peptidase_S1_PA.
DR   InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR   InterPro; IPR001254; Trypsin_dom.
DR   Pfam; PF00089; Trypsin; 1.
DR   SUPFAM; SSF50494; SSF50494; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hydrolase; Protease; Secreted; Serine protease.
FT   CHAIN           1..>31
FT                   /note="Chymotrypsin"
FT                   /id="PRO_0000088675"
FT   DOMAIN          1..>31
FT                   /note="Peptidase S1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00274"
FT   NON_TER         31
SQ   SEQUENCE   31 AA;  3287 MW;  6CCD1D09067D1D78 CRC64;
     IVGGVEAVPG VWPYQAALFI IDMYFCGGSL I