ID   CTSL2_XENTR             Reviewed;         466 AA.
AC   Q66KM5;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=CTD small phosphatase-like protein 2;
DE            Short=CTDSP-like 2;
DE            EC=3.1.3.-;
GN   Name=ctdspl2;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable phosphatase. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CTDSPL2 family. {ECO:0000305}.
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DR   EMBL; BC080328; AAH80328.1; -; mRNA.
DR   RefSeq; NP_001008438.1; NM_001008438.1.
DR   RefSeq; XP_012814332.1; XM_012958878.2.
DR   AlphaFoldDB; Q66KM5; -.
DR   SMR; Q66KM5; -.
DR   PaxDb; Q66KM5; -.
DR   DNASU; 493278; -.
DR   Ensembl; ENSXETT00000017145; ENSXETP00000017145; ENSXETG00000007843.
DR   GeneID; 493278; -.
DR   KEGG; xtr:493278; -.
DR   CTD; 51496; -.
DR   Xenbase; XB-GENE-950101; ctdspl2.
DR   eggNOG; KOG1605; Eukaryota.
DR   HOGENOM; CLU_034042_4_0_1; -.
DR   InParanoid; Q66KM5; -.
DR   OMA; PSCEEDW; -.
DR   OrthoDB; 1176152at2759; -.
DR   PhylomeDB; Q66KM5; -.
DR   TreeFam; TF354278; -.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000007843; Expressed in 4-cell stage embryo and 14 other tissues.
DR   GO; GO:0004721; F:phosphoprotein phosphatase activity; IBA:GO_Central.
DR   Gene3D; 3.40.50.1000; -; 1.
DR   InterPro; IPR011948; Dullard_phosphatase.
DR   InterPro; IPR004274; FCP1_dom.
DR   InterPro; IPR036412; HAD-like_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   Pfam; PF03031; NIF; 1.
DR   SMART; SM00577; CPDc; 1.
DR   SUPFAM; SSF56784; SSF56784; 1.
DR   TIGRFAMs; TIGR02251; HIF-SF_euk; 1.
DR   PROSITE; PS50969; FCP1; 1.
PE   2: Evidence at transcript level;
KW   Hydrolase; Protein phosphatase; Reference proteome.
FT   CHAIN           1..466
FT                   /note="CTD small phosphatase-like protein 2"
FT                   /id="PRO_0000331472"
FT   DOMAIN          283..442
FT                   /note="FCP1 homology"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00336"
FT   REGION          1..136
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..238
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        61..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..136
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   466 AA;  52949 MW;  EF6270B5ED0463FC CRC64;
     MRLRTRKGSP RSSHGAAGRT ARCKRKHSEE DEEEESQLIE EDKLPKQETG LLSTIKNFIK
     GSTNKEDREN PAKRSRVERD LDNNLITSTP RTGDKPSKPI ARVRRKSQVN GEATGYEVSQ
     HMKQNGKLED LPSTTSPPRT TLLGTIFSPV FNFFSPANKN GTSGSDSPGQ AVEAEEIVKQ
     LDMEKVDEFS TSTATNGASY PSLAAPVRST ASSWLEGTED SPEREIPPLT APVSPESGYS
     SAHAEAAYEE DWEVFDPYYF IKHVPPLTEE QLNRKPALPL KTRSTPEFSL VLDLDETLVH
     CSLNELEDAA LTFPVLFQDV IYQVYVRLRP FFREFLERMS QIYEIILFTA SKKVYADKLL
     NILDPKKRLV RHRLFREHCV CVQGNYIKDL NILGRDLSKT IIIDNSPQAF AYQLSNGIPI
     ESWFMDKNDK ELLKLVPFLE NLVELNEDVR PHIRDRFRLH DCLPPD