ID   CTSP2_CRODU             Reviewed;          63 AA.
AC   Q6HAA2;
DT   13-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Crotasin;
DE   Flags: Precursor;
GN   Name=Cts-p2 {ECO:0000312|EMBL:AAT47437.1};
OS   Crotalus durissus terrificus (South American rattlesnake).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus.
OX   NCBI_TaxID=8732;
RN   [1] {ECO:0000305, ECO:0000312|EMBL:AAT47437.1}
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND TISSUE SPECIFICITY.
RC   TISSUE=Liver {ECO:0000312|EMBL:AAT47437.1};
RX   PubMed=15284009; DOI=10.1016/j.toxicon.2004.02.023;
RA   Radis-Baptista G., Kubo T., Oguiura N., Prieto da Silva A.R.B.,
RA   Hayashi M.A.F., Oliveira E.B., Yamane T.;
RT   "Identification of crotasin, a crotamine-related gene of Crotalus durissus
RT   terrificus.";
RL   Toxicon 43:751-759(2004).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Highly expressed in pancreas, heart, liver, brain
CC       and kidney. Expressed to a low extent in the venom gland.
CC       {ECO:0000269|PubMed:15284009}.
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DR   EMBL; AF250212; AAT47437.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q6HAA2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Disulfide bond; Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..63
FT                   /note="Crotasin"
FT                   /id="PRO_0000035186"
FT   DISULFID        26..56
FT                   /evidence="ECO:0000250|UniProtKB:P24333"
FT   DISULFID        33..50
FT                   /evidence="ECO:0000250|UniProtKB:P24333"
FT   DISULFID        38..57
FT                   /evidence="ECO:0000250|UniProtKB:P24333"
SQ   SEQUENCE   63 AA;  7142 MW;  C42B7D65CE4C1445 CRC64;
     MKILYLLSAF LFLAFLSESG NAQPQCRWLD GFCHSSPCPS GTTSIGQQDC LWYESCCIPR
     YEK