ID   CTSR_STAAM              Reviewed;         153 AA.
AC   Q99W81;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Transcriptional regulator CtsR;
GN   Name=ctsR; OrderedLocusNames=SAV0522;
OS   Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=158878;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Mu50 / ATCC 700699;
RX   PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA   Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA   Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA   Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA   Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA   Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA   Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA   Hiramatsu K.;
RT   "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL   Lancet 357:1225-1240(2001).
CC   -!- FUNCTION: Negative regulator of clpC, clpB and clpP transcription by
CC       binding directly and specifically to their promoter region.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CtsR family. {ECO:0000305}.
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DR   EMBL; BA000017; BAB56684.1; -; Genomic_DNA.
DR   RefSeq; WP_000551762.1; NC_002758.2.
DR   AlphaFoldDB; Q99W81; -.
DR   SMR; Q99W81; -.
DR   PaxDb; Q99W81; -.
DR   EnsemblBacteria; BAB56684; BAB56684; SAV0522.
DR   KEGG; sav:SAV0522; -.
DR   HOGENOM; CLU_118139_0_0_9; -.
DR   OMA; FRCAPSQ; -.
DR   PhylomeDB; Q99W81; -.
DR   BioCyc; SAUR158878:SAV_RS02930-MON; -.
DR   Proteomes; UP000002481; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1200.150; -; 1.
DR   Gene3D; 3.30.56.130; -; 1.
DR   InterPro; IPR008463; CtsR.
DR   InterPro; IPR041473; CtsR_C.
DR   InterPro; IPR041908; CtsR_C_sf.
DR   InterPro; IPR040465; CtsR_N.
DR   InterPro; IPR041902; CtsR_N_sf.
DR   PANTHER; PTHR40028; PTHR40028; 1.
DR   Pfam; PF05848; CtsR; 1.
DR   Pfam; PF17727; CtsR_C; 1.
DR   PIRSF; PIRSF010607; Txn_repr_CtsR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..153
FT                   /note="Transcriptional regulator CtsR"
FT                   /id="PRO_0000274132"
SQ   SEQUENCE   153 AA;  17842 MW;  2EA1D6892A9FE62A CRC64;
     MHNMSDIIEQ YIKRLFEESN EDVVEIQRAN IAQRFDCVPS QLNYVIKTRF TNEHGYEIES
     KRGGGGYIRI TKIENKDATG YINHLLQLIG PSISQQQAYY IIDGLLDKML INEREAKMIQ
     AVIDRETLSM DMVSRDIIRA NILKRLLPVI NYY