ID   CTSR_STAAW              Reviewed;         153 AA.
AC   Q7A1R4;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 86.
DE   RecName: Full=Transcriptional regulator CtsR;
GN   Name=ctsR; OrderedLocusNames=MW0477;
OS   Staphylococcus aureus (strain MW2).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=196620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MW2;
RX   PubMed=12044378; DOI=10.1016/s0140-6736(02)08713-5;
RA   Baba T., Takeuchi F., Kuroda M., Yuzawa H., Aoki K., Oguchi A., Nagai Y.,
RA   Iwama N., Asano K., Naimi T., Kuroda H., Cui L., Yamamoto K., Hiramatsu K.;
RT   "Genome and virulence determinants of high virulence community-acquired
RT   MRSA.";
RL   Lancet 359:1819-1827(2002).
CC   -!- FUNCTION: Negative regulator of clpC, clpB and clpP transcription by
CC       binding directly and specifically to their promoter region.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CtsR family. {ECO:0000305}.
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DR   EMBL; BA000033; BAB94342.1; -; Genomic_DNA.
DR   RefSeq; WP_000551762.1; NC_003923.1.
DR   AlphaFoldDB; Q7A1R4; -.
DR   SMR; Q7A1R4; -.
DR   EnsemblBacteria; BAB94342; BAB94342; BAB94342.
DR   KEGG; sam:MW0477; -.
DR   HOGENOM; CLU_118139_0_0_9; -.
DR   OMA; FRCAPSQ; -.
DR   Proteomes; UP000000418; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1200.150; -; 1.
DR   Gene3D; 3.30.56.130; -; 1.
DR   InterPro; IPR008463; CtsR.
DR   InterPro; IPR041473; CtsR_C.
DR   InterPro; IPR041908; CtsR_C_sf.
DR   InterPro; IPR040465; CtsR_N.
DR   InterPro; IPR041902; CtsR_N_sf.
DR   PANTHER; PTHR40028; PTHR40028; 1.
DR   Pfam; PF05848; CtsR; 1.
DR   Pfam; PF17727; CtsR_C; 1.
DR   PIRSF; PIRSF010607; Txn_repr_CtsR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..153
FT                   /note="Transcriptional regulator CtsR"
FT                   /id="PRO_0000274136"
SQ   SEQUENCE   153 AA;  17842 MW;  2EA1D6892A9FE62A CRC64;
     MHNMSDIIEQ YIKRLFEESN EDVVEIQRAN IAQRFDCVPS QLNYVIKTRF TNEHGYEIES
     KRGGGGYIRI TKIENKDATG YINHLLQLIG PSISQQQAYY IIDGLLDKML INEREAKMIQ
     AVIDRETLSM DMVSRDIIRA NILKRLLPVI NYY