ID   CTSR_STAES              Reviewed;         153 AA.
AC   Q8CQ89;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Transcriptional regulator CtsR;
GN   Name=ctsR; OrderedLocusNames=SE_0284;
OS   Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=176280;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 12228 / FDA PCI 1200;
RX   PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA   Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA   Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA   Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT   "Genome-based analysis of virulence genes in a non-biofilm-forming
RT   Staphylococcus epidermidis strain (ATCC 12228).";
RL   Mol. Microbiol. 49:1577-1593(2003).
CC   -!- FUNCTION: Negative regulator of clpC, clpB and clpP transcription by
CC       binding directly and specifically to their promoter region.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CtsR family. {ECO:0000305}.
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DR   EMBL; AE015929; AAO03881.1; -; Genomic_DNA.
DR   RefSeq; NP_763839.1; NC_004461.1.
DR   RefSeq; WP_001832288.1; NZ_WBME01000014.1.
DR   AlphaFoldDB; Q8CQ89; -.
DR   SMR; Q8CQ89; -.
DR   STRING; 176280.SE_0284; -.
DR   EnsemblBacteria; AAO03881; AAO03881; SE_0284.
DR   GeneID; 50019550; -.
DR   KEGG; sep:SE_0284; -.
DR   PATRIC; fig|176280.10.peg.260; -.
DR   eggNOG; COG4463; Bacteria.
DR   HOGENOM; CLU_118139_0_0_9; -.
DR   OMA; FRCAPSQ; -.
DR   Proteomes; UP000001411; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1200.150; -; 1.
DR   Gene3D; 3.30.56.130; -; 1.
DR   InterPro; IPR008463; CtsR.
DR   InterPro; IPR041473; CtsR_C.
DR   InterPro; IPR041908; CtsR_C_sf.
DR   InterPro; IPR040465; CtsR_N.
DR   InterPro; IPR041902; CtsR_N_sf.
DR   PANTHER; PTHR40028; PTHR40028; 1.
DR   Pfam; PF05848; CtsR; 1.
DR   Pfam; PF17727; CtsR_C; 1.
DR   PIRSF; PIRSF010607; Txn_repr_CtsR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..153
FT                   /note="Transcriptional regulator CtsR"
FT                   /id="PRO_0000274138"
SQ   SEQUENCE   153 AA;  17784 MW;  4F72A3EA209764B7 CRC64;
     MHNMSDIIEQ YIKRLFEEAD EDVVEIQRAH IAQRFDCVPS QLNYVIKTRF TNEHGYEIES
     KRGGGGYIRI TKIENKDATG YINHLLQLIG PSISQQQGYY VIDGLLDKGL INEREAKMIQ
     TIIDRETLKM DVVARDIIRA NILKRLLPVI NYY