ID   CTSR_STAHJ              Reviewed;         153 AA.
AC   Q4L3I1;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-AUG-2005, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Transcriptional regulator CtsR;
GN   Name=ctsR; OrderedLocusNames=SH2487;
OS   Staphylococcus haemolyticus (strain JCSC1435).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=279808;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCSC1435;
RX   PubMed=16237012; DOI=10.1128/jb.187.21.7292-7308.2005;
RA   Takeuchi F., Watanabe S., Baba T., Yuzawa H., Ito T., Morimoto Y.,
RA   Kuroda M., Cui L., Takahashi M., Ankai A., Baba S., Fukui S., Lee J.C.,
RA   Hiramatsu K.;
RT   "Whole-genome sequencing of Staphylococcus haemolyticus uncovers the
RT   extreme plasticity of its genome and the evolution of human-colonizing
RT   staphylococcal species.";
RL   J. Bacteriol. 187:7292-7308(2005).
CC   -!- FUNCTION: Negative regulator of clpC, clpB and clpP transcription by
CC       binding directly and specifically to their promoter region.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CtsR family. {ECO:0000305}.
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DR   EMBL; AP006716; BAE05796.1; -; Genomic_DNA.
DR   RefSeq; WP_011276739.1; NC_007168.1.
DR   AlphaFoldDB; Q4L3I1; -.
DR   SMR; Q4L3I1; -.
DR   STRING; 279808.SH2487; -.
DR   EnsemblBacteria; BAE05796; BAE05796; SH2487.
DR   GeneID; 58061494; -.
DR   KEGG; sha:SH2487; -.
DR   eggNOG; COG4463; Bacteria.
DR   HOGENOM; CLU_118139_0_0_9; -.
DR   OMA; FRCAPSQ; -.
DR   OrthoDB; 2005536at2; -.
DR   Proteomes; UP000000543; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.1200.150; -; 1.
DR   Gene3D; 3.30.56.130; -; 1.
DR   InterPro; IPR008463; CtsR.
DR   InterPro; IPR041473; CtsR_C.
DR   InterPro; IPR041908; CtsR_C_sf.
DR   InterPro; IPR040465; CtsR_N.
DR   InterPro; IPR041902; CtsR_N_sf.
DR   PANTHER; PTHR40028; PTHR40028; 1.
DR   Pfam; PF05848; CtsR; 1.
DR   Pfam; PF17727; CtsR_C; 1.
DR   PIRSF; PIRSF010607; Txn_repr_CtsR; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Repressor; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..153
FT                   /note="Transcriptional regulator CtsR"
FT                   /id="PRO_0000274139"
SQ   SEQUENCE   153 AA;  17759 MW;  3A77EA24CEBAAFD7 CRC64;
     MHNMSDIIEQ YIKKLFEESN EDVVEIQRAN IAQRFDCVPS QLNYVIKTRF TNEHGYEIES
     KRGGGGYIRI TKIENKDATG YINHLLQIIG PSISQQQAYY ILDGLLDKGL ISEREARMIQ
     VIVDRETLKM DVVARDIIRA NILKRLLPII NFY