ID   CTXL_ACRMI              Reviewed;         473 AA.
AC   B7W114;
DT   09-JUL-2014, integrated into UniProtKB/Swiss-Prot.
DT   09-JUL-2014, sequence version 1.
DT   25-MAY-2022, entry version 13.
DE   RecName: Full=Cephalotoxin-like protein {ECO:0000303|PubMed:23765379};
DE   Flags: Precursor; Fragment;
OS   Acropora millepora (Staghorn coral) (Heteropora millepora).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Scleractinia;
OC   Astrocoeniina; Acroporidae; Acropora.
OX   NCBI_TaxID=45264;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=22490231; DOI=10.1111/j.1365-294x.2012.05554.x;
RA   Moya A., Huisman L., Ball E.E., Hayward D.C., Grasso L.C., Chua C.M.,
RA   Woo H.N., Gattuso J.P., Foret S., Miller D.J.;
RT   "Whole transcriptome analysis of the coral Acropora millepora reveals
RT   complex responses to CO(2)-driven acidification during the initiation of
RT   calcification.";
RL   Mol. Ecol. 21:2440-2454(2012).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 29-54; 210-222; 226-238; 274-283 AND 323-331, TISSUE
RP   SPECIFICITY, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX   PubMed=23765379; DOI=10.1093/molbev/mst109;
RA   Ramos-Silva P., Kaandorp J., Huisman L., Marie B., Zanella-Cleon I.,
RA   Guichard N., Miller D.J., Marin F.;
RT   "The skeletal proteome of the coral Acropora millepora: the evolution of
RT   calcification by co-option and domain shuffling.";
RL   Mol. Biol. Evol. 30:2099-2112(2013).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:23765379}.
CC   -!- TISSUE SPECIFICITY: Component of the acid-insoluble and acid-soluble
CC       organic matrix of the aragonitic skeleton (at protein level).
CC       {ECO:0000269|PubMed:23765379}.
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DR   EMBL; JR986059; -; NOT_ANNOTATED_CDS; mRNA.
DR   AlphaFoldDB; B7W114; -.
DR   SMR; B7W114; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR039051; SE-CTX-like.
DR   PANTHER; PTHR40472; PTHR40472; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Direct protein sequencing; Secreted; Signal.
FT   SIGNAL          <1..21
FT                   /evidence="ECO:0000255"
FT   CHAIN           22..>473
FT                   /note="Cephalotoxin-like protein"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000429497"
FT   COILED          40..60
FT                   /evidence="ECO:0000255"
FT   COILED          116..147
FT                   /evidence="ECO:0000255"
FT   NON_TER         1
FT                   /evidence="ECO:0000305"
FT   NON_TER         473
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   473 AA;  54401 MW;  C385D96AE23AEBA6 CRC64;
     RWLGWQKFCW ISCLFSSISS GLDPGEQAKV TTALDTAQFA INAINEEYIA QAKAIEEALK
     VSTQARSADL LRRQTELAKF GSKVGKALKA VQAASAIASF VFTFFMPSEL DVITSLINER
     FNEVNAKLDR IDEKLDEMEK SIKADTAFNV FLSAWIKWEY KVRNGAKKLS DIRKAMGTKT
     QRIDQVKLAE EYVKYYETNN LDGNVLSLYR MAALPESITQ RNIFDRFIAQ FGCDITKLSE
     LMILVQNIMT SAGQQKLTYY YFKGDQSRAN SSFKDIQMYF FKIRQGFDDR VWHCRRNSLD
     YAKRDANKIL KNMRGSSRES IVRAIFNELK VKYPWYTWAV AAVKSDRPRI RGLELRGSTY
     FRLEDRSDAK KVKGYFVVYE DTRSSASCSD ITQAKTLLVF KKCDGCNSDY IYAADNILSK
     KRCGESTLER LVDFKQQCPV CHRWPYSITC YCANRVKQDS QNMGLYCISS QHH