ID   CTXN1_MOUSE             Reviewed;          82 AA.
AC   Q8K129;
DT   15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2002, sequence version 1.
DT   03-AUG-2022, entry version 112.
DE   RecName: Full=Cortexin-1;
GN   Name=Ctxn1; Synonyms=Ctxn;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Colon;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- FUNCTION: May mediate extracellular or intracellular signaling of
CC       cortical neurons during forebrain development. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cortexin family. {ECO:0000305}.
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DR   EMBL; BC028881; AAH28881.1; -; mRNA.
DR   CCDS; CCDS40211.1; -.
DR   RefSeq; NP_899138.1; NM_183315.2.
DR   AlphaFoldDB; Q8K129; -.
DR   SMR; Q8K129; -.
DR   IntAct; Q8K129; 1.
DR   STRING; 10090.ENSMUSP00000057115; -.
DR   iPTMnet; Q8K129; -.
DR   PhosphoSitePlus; Q8K129; -.
DR   PaxDb; Q8K129; -.
DR   PRIDE; Q8K129; -.
DR   ProteomicsDB; 284060; -.
DR   Antibodypedia; 2649; 22 antibodies from 8 providers.
DR   DNASU; 330695; -.
DR   Ensembl; ENSMUST00000053252; ENSMUSP00000057115; ENSMUSG00000048644.
DR   GeneID; 330695; -.
DR   KEGG; mmu:330695; -.
DR   UCSC; uc009ktp.2; mouse.
DR   CTD; 404217; -.
DR   MGI; MGI:88566; Ctxn1.
DR   VEuPathDB; HostDB:ENSMUSG00000048644; -.
DR   eggNOG; ENOG502S3S8; Eukaryota.
DR   GeneTree; ENSGT00940000154412; -.
DR   HOGENOM; CLU_193122_0_0_1; -.
DR   InParanoid; Q8K129; -.
DR   OMA; ILMVRCF; -.
DR   PhylomeDB; Q8K129; -.
DR   TreeFam; TF333403; -.
DR   BioGRID-ORCS; 330695; 2 hits in 74 CRISPR screens.
DR   ChiTaRS; Ctxn1; mouse.
DR   PRO; PR:Q8K129; -.
DR   Proteomes; UP000000589; Chromosome 8.
DR   RNAct; Q8K129; protein.
DR   Bgee; ENSMUSG00000048644; Expressed in piriform cortex and 206 other tissues.
DR   ExpressionAtlas; Q8K129; baseline and differential.
DR   Genevisible; Q8K129; MM.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR020066; Cortexin.
DR   PANTHER; PTHR16736; PTHR16736; 1.
DR   Pfam; PF11057; Cortexin; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..82
FT                   /note="Cortexin-1"
FT                   /id="PRO_0000079501"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   82 AA;  9059 MW;  17B789079CF0E0D4 CRC64;
     MSSAWTLSPE PLPPSTGPPV GAGLDVEQRT VFAFVLCLLV VLVLLMVRCV RILLDPYSRM
     PASSWTDHKE ALERGQFDYA LV