ID   CTXN1_RAT               Reviewed;          82 AA.
AC   P41237;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Cortexin-1;
GN   Name=Ctxn1; Synonyms=Ctxn;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Brain;
RX   PubMed=8336151; DOI=10.1111/j.1471-4159.1993.tb02183.x;
RA   Coulter P.M. II, Bautista E.A., Margulies J.E., Watson J.B.;
RT   "Identification of cortexin: a novel, neuron-specific, 82-residue membrane
RT   protein enriched in rodent cerebral cortex.";
RL   J. Neurochem. 61:756-759(1993).
CC   -!- FUNCTION: May mediate extracellular or intracellular signaling of
CC       cortical neurons during forebrain development.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Neuron specific.
CC   -!- SIMILARITY: Belongs to the cortexin family. {ECO:0000305}.
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DR   EMBL; L15011; -; NOT_ANNOTATED_CDS; mRNA.
DR   PIR; JH0814; JH0814.
DR   RefSeq; NP_001103405.1; NM_001109935.1.
DR   AlphaFoldDB; P41237; -.
DR   SMR; P41237; -.
DR   STRING; 10116.ENSRNOP00000001399; -.
DR   PaxDb; P41237; -.
DR   GeneID; 29145; -.
DR   KEGG; rno:29145; -.
DR   UCSC; RGD:2449; rat.
DR   CTD; 404217; -.
DR   RGD; 2449; Ctxn1.
DR   eggNOG; ENOG502S3S8; Eukaryota.
DR   HOGENOM; CLU_193122_0_0_1; -.
DR   InParanoid; P41237; -.
DR   OMA; ILMVRCF; -.
DR   PhylomeDB; P41237; -.
DR   TreeFam; TF333403; -.
DR   PRO; PR:P41237; -.
DR   Proteomes; UP000002494; Chromosome 12.
DR   Bgee; ENSRNOG00000001057; Expressed in frontal cortex and 19 other tissues.
DR   Genevisible; P41237; RN.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007417; P:central nervous system development; NAS:RGD.
DR   InterPro; IPR020066; Cortexin.
DR   PANTHER; PTHR16736; PTHR16736; 1.
DR   Pfam; PF11057; Cortexin; 1.
PE   2: Evidence at transcript level;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..82
FT                   /note="Cortexin-1"
FT                   /id="PRO_0000079502"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   82 AA;  9069 MW;  B43A07040D10F5C2 CRC64;
     MSAPWTLSPE PLPPSTGPPV GAGLDVEQRT VFAFVLCLLV VLVLLMVRCV RILLDPYSRM
     PASSWTDHKE ALERGQFDYA LV