ID   CTXN2_MOUSE             Reviewed;          81 AA.
AC   Q3URE8;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   17-APR-2007, sequence version 2.
DT   03-AUG-2022, entry version 91.
DE   RecName: Full=Cortexin-2;
GN   Name=Ctxn2;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Hippocampus;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the cortexin family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAE24740.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AK141570; BAE24740.1; ALT_INIT; mRNA.
DR   CCDS; CCDS50692.1; -.
DR   RefSeq; NP_001156406.2; NM_001162934.1.
DR   RefSeq; XP_006499896.1; XM_006499833.2.
DR   RefSeq; XP_006499897.1; XM_006499834.3.
DR   RefSeq; XP_006499898.1; XM_006499835.2.
DR   AlphaFoldDB; Q3URE8; -.
DR   SMR; Q3URE8; -.
DR   STRING; 10090.ENSMUSP00000097051; -.
DR   PaxDb; Q3URE8; -.
DR   PRIDE; Q3URE8; -.
DR   Antibodypedia; 65141; 5 antibodies from 5 providers.
DR   Ensembl; ENSMUST00000238377; ENSMUSP00000158847; ENSMUSG00000074872.
DR   Ensembl; ENSMUST00000238754; ENSMUSP00000158834; ENSMUSG00000074872.
DR   GeneID; 381418; -.
DR   KEGG; mmu:381418; -.
DR   UCSC; uc008mce.2; mouse.
DR   CTD; 399697; -.
DR   MGI; MGI:2139444; Ctxn2.
DR   VEuPathDB; HostDB:ENSMUSG00000074872; -.
DR   eggNOG; ENOG502S3V3; Eukaryota.
DR   GeneTree; ENSGT00940000154412; -.
DR   InParanoid; Q3URE8; -.
DR   OMA; ASMSVNK; -.
DR   OrthoDB; 1622786at2759; -.
DR   PhylomeDB; Q3URE8; -.
DR   TreeFam; TF333403; -.
DR   BioGRID-ORCS; 381418; 2 hits in 71 CRISPR screens.
DR   PRO; PR:Q3URE8; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q3URE8; protein.
DR   Bgee; ENSMUSG00000074872; Expressed in substantia nigra and 85 other tissues.
DR   ExpressionAtlas; Q3URE8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR020066; Cortexin.
DR   PANTHER; PTHR16736; PTHR16736; 1.
DR   Pfam; PF11057; Cortexin; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..81
FT                   /note="Cortexin-2"
FT                   /id="PRO_0000284617"
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   81 AA;  8987 MW;  481474B113BD6D58 CRC64;
     MSSTYCGNSS AKMSVHEVSE SSLSLEQKTG FAFVGILCIF LGLLIIRCFK ILLDPYSSMP
     SSTWEDEVEE FDKGTFEYAL A