CTXN3_MOUSE
ID CTXN3_MOUSE Reviewed; 80 AA.
AC Q8BXZ0;
DT 17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Cortexin-3;
GN Name=Ctxn3;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Cerebellum;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the cortexin family. {ECO:0000305}.
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DR EMBL; AK042789; BAC31367.1; -; mRNA.
DR CCDS; CCDS50294.1; -.
DR RefSeq; NP_001128169.1; NM_001134697.1.
DR RefSeq; XP_006526201.1; XM_006526138.2.
DR RefSeq; XP_006526202.1; XM_006526139.1.
DR RefSeq; XP_006526203.1; XM_006526140.3.
DR RefSeq; XP_011245283.1; XM_011246981.2.
DR AlphaFoldDB; Q8BXZ0; -.
DR SMR; Q8BXZ0; -.
DR STRING; 10090.ENSMUSP00000089507; -.
DR PhosphoSitePlus; Q8BXZ0; -.
DR PaxDb; Q8BXZ0; -.
DR PRIDE; Q8BXZ0; -.
DR ProteomicsDB; 279297; -.
DR Ensembl; ENSMUST00000091892; ENSMUSP00000089507; ENSMUSG00000069372.
DR Ensembl; ENSMUST00000209786; ENSMUSP00000147982; ENSMUSG00000069372.
DR GeneID; 629147; -.
DR KEGG; mmu:629147; -.
DR UCSC; uc008ezd.2; mouse.
DR CTD; 613212; -.
DR MGI; MGI:3642816; Ctxn3.
DR VEuPathDB; HostDB:ENSMUSG00000069372; -.
DR eggNOG; ENOG502S3V3; Eukaryota.
DR GeneTree; ENSGT00940000154412; -.
DR HOGENOM; CLU_193122_0_0_1; -.
DR InParanoid; Q8BXZ0; -.
DR OMA; RKLWDYS; -.
DR OrthoDB; 1640476at2759; -.
DR PhylomeDB; Q8BXZ0; -.
DR TreeFam; TF333403; -.
DR BioGRID-ORCS; 629147; 3 hits in 69 CRISPR screens.
DR PRO; PR:Q8BXZ0; -.
DR Proteomes; UP000000589; Chromosome 18.
DR RNAct; Q8BXZ0; protein.
DR Bgee; ENSMUSG00000069372; Expressed in olfactory epithelium and 126 other tissues.
DR ExpressionAtlas; Q8BXZ0; baseline and differential.
DR Genevisible; Q8BXZ0; MM.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR020066; Cortexin.
DR PANTHER; PTHR16736; PTHR16736; 1.
DR Pfam; PF11057; Cortexin; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..80
FT /note="Cortexin-3"
FT /id="PRO_0000284514"
FT TRANSMEM 28..48
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 80 AA; 8832 MW; 6856210FAB1AF4D7 CRC64;
MDGGQPVPSP LVPLGNGSDY SMSLEQKTTF VFVILLFIFL GILIVRCFRI LLDPYRSMPT
STWADGLEGL EKGQFDHALA