ID   CU08_LOCMI              Reviewed;         148 AA.
AC   P11734;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Cuticle protein 8;
DE   AltName: Full=LM-ACP 8;
DE            Short=LM-8;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=2590176; DOI=10.1042/bj2620923;
RA   Klarskov K., Hoejrup P., Andersen S.O., Roepstorff P.;
RT   "Plasma-desorption mass spectrometry as an aid in protein sequence
RT   determination. Application of the method on a cuticular protein from the
RT   migratory locust (Locusta migratoria).";
RL   Biochem. J. 262:923-930(1989).
RN   [2]
RP   PROTEIN SEQUENCE OF 1-56.
RX   PubMed=3943519; DOI=10.1111/j.1432-1033.1986.tb09371.x;
RA   Hoejrup P., Andersen S.O., Roepstorff P.;
RT   "Isolation, characterization, and N-terminal sequence studies of cuticular
RT   proteins from the migratory locust, Locusta migratoria.";
RL   Eur. J. Biochem. 154:153-159(1986).
CC   -!- FUNCTION: Component of the cuticle of migratory locust which contains
CC       more than 100 different structural proteins.
CC   -!- DOMAIN: The tetrapeptide (A-A-P-[AV]) repeats found throughout the
CC       protein are also present in many proteins constituting the protective
CC       envelope of other species.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   PIR; S05638; S05638.
DR   AlphaFoldDB; P11734; -.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR   InterPro; IPR000618; Insect_cuticle.
DR   Pfam; PF00379; Chitin_bind_4; 1.
DR   PRINTS; PR00947; CUTICLE.
DR   PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR   PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE   1: Evidence at protein level;
KW   Cuticle; Direct protein sequencing; Repeat.
FT   CHAIN           1..148
FT                   /note="Cuticle protein 8"
FT                   /id="PRO_0000196093"
FT   REPEAT          16..19
FT                   /note="1"
FT   REPEAT          22
FT                   /note="2"
FT   REPEAT          28..31
FT                   /note="3"
FT   REPEAT          37..40
FT                   /note="4"
FT   REPEAT          44..47
FT                   /note="5"
FT   DOMAIN          58..128
FT                   /note="Chitin-binding type R&R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
SQ   SEQUENCE   148 AA;  15224 MW;  C6EADC27C593ACE6 CRC64;
     IEDEYGNVLH ASGGYAAPAA YAAPVAYAAP VAKAVVAAPA VAYAAPVAKA VVAEPVAYPK
     YEFNYGVHDA HTGDIKQQSE ARDGDVVKGS YSLVEPDGST RTVEYQADDH NGFNAVVHRT
     PGTHPVAVAP VAVAHAPVAV AHAPIAYH