ID   CU15_MANSE              Reviewed;         106 AA.
AC   Q94984;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Cuticle protein CP14.6;
DE   AltName: Full=MSCP14.6;
DE   Flags: Precursor;
GN   Name=CP14.6;
OS   Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Sphingidae; Sphinginae; Sphingini; Manduca.
OX   NCBI_TaxID=7130;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA].
RC   TISSUE=Epidermis;
RX   PubMed=9090118; DOI=10.1016/s0965-1748(96)00090-2;
RA   Rebers J.E., Niu J., Riddiford L.M.;
RT   "Structure and spatial expression of the Manduca sexta MSCP14.6 cuticle
RT   gene.";
RL   Insect Biochem. Mol. Biol. 27:229-240(1997).
CC   -!- FUNCTION: Component of the cuticle of tobacco hornworm.
CC   -!- DEVELOPMENTAL STAGE: Expressed throughout the epidermis in larvae with
CC       the exception of the bristle cells. Only found in the flexible
CC       intersegmental cuticle during endocuticular deposition in the pharate
CC       pupae. Restricted to epidermal cells at the muscle attachment sites in
CC       the adult.
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DR   EMBL; U65902; AAC47496.1; -; mRNA.
DR   EMBL; U65901; AAC47495.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q94984; -.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR   InterPro; IPR000618; Insect_cuticle.
DR   Pfam; PF00379; Chitin_bind_4; 1.
DR   PRINTS; PR00947; CUTICLE.
DR   PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR   PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE   2: Evidence at transcript level;
KW   Cuticle; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..106
FT                   /note="Cuticle protein CP14.6"
FT                   /id="PRO_0000006408"
FT   DOMAIN          37..106
FT                   /note="Chitin-binding type R&R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
SQ   SEQUENCE   106 AA;  11014 MW;  C3DAE0AE3F685A71 CRC64;
     MKSFFVVALL VAAAAAAPAN PDADAVIVRY DADQGDPQHY SYSVETSNGI AFSEEGALKN
     VGSENEANSV RGSYAYVGPD GVTYSVVYIA DENGFQPQGA HLPVAA