CU20_TENMO
ID CU20_TENMO Reviewed; 208 AA.
AC P26967;
DT 01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1992, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Adult-specific cuticular protein ACP-20;
DE Flags: Precursor;
GN Name=ACP20;
OS Tenebrio molitor (Yellow mealworm beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrio.
OX NCBI_TaxID=7067;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 95-107.
RX PubMed=1606964; DOI=10.1111/j.1432-1033.1992.tb16989.x;
RA Charles J.-P., Bouhin H., Quennedey B., Courrent A., Delachambre J.;
RT "cDNA cloning and deduced amino acid sequence of a major, glycine-rich
RT cuticular protein from the coleopteran Tenebrio molitor. Temporal and
RT spatial distribution of the transcript during metamorphosis.";
RL Eur. J. Biochem. 206:813-819(1992).
CC -!- FUNCTION: Cuticular proteins play a significant role in determining the
CC physical properties of cuticles.
CC -!- TISSUE SPECIFICITY: Epidermal regions synthesizing hard cuticle.
CC -!- DEVELOPMENTAL STAGE: Preecdysial adult cuticle deposition.
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DR EMBL; X63459; CAA45057.1; -; mRNA.
DR PIR; S23463; S23463.
DR AlphaFoldDB; P26967; -.
DR GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR InterPro; IPR000618; Insect_cuticle.
DR Pfam; PF00379; Chitin_bind_4; 1.
DR PRINTS; PR00947; CUTICLE.
DR PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE 1: Evidence at protein level;
KW Cuticle; Direct protein sequencing; Repeat; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..208
FT /note="Adult-specific cuticular protein ACP-20"
FT /id="PRO_0000006414"
FT REPEAT 34..43
FT /note="1"
FT DOMAIN 64..135
FT /note="Chitin-binding type R&R"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
FT REPEAT 171..180
FT /note="2"
FT REGION 34..180
FT /note="2 X 10 AA repeats"
SQ SEQUENCE 208 AA; 20070 MW; 0A1364F07CD2747E CRC64;
MLVQITALAF LAGIASAGVV VGGYGDGVGV GLGGLGGGLG GVGVGLGGVG VVGGGHGVVD
LHTPAHYQFK YGVEDHRTGD RKQQAEVRVG DVVKGEYSLA EPDGTVRVVK YTADDHNGFN
AVVSRVGHAV HPQVLVRKAV VPVATHGVVG VGGLGGLGGV GLGGVGLGGV GLGGGLGGVG
LLGGRGGLDR GILGGHGGSE LKFKRALI