ID   CU21_LOCMI              Reviewed;         169 AA.
AC   P81225; P81226;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   15-JUL-1998, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Cuticle protein 21;
DE   AltName: Full=LM-ACP 21;
GN   Name=ACP21;
OS   Locusta migratoria (Migratory locust).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC   Acridoidea; Acrididae; Oedipodinae; Locusta.
OX   NCBI_TaxID=7004;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Cuticle;
RX   PubMed=9920393; DOI=10.1016/s0167-4838(98)00227-1;
RA   Jensen C., Andersen S.O., Roepstorff P.;
RT   "Primary structure of two major cuticular proteins from the migratory
RT   locust, Locusta migratoria, and their identification in polyacrylamide gels
RT   by mass spectrometry.";
RL   Biochim. Biophys. Acta 1429:151-162(1998).
CC   -!- FUNCTION: Component of the cuticle of migratory locust which contains
CC       more than 100 different structural proteins.
CC   -!- DOMAIN: The tetrapeptide (A-A-P-[AV]) repeats found throughout the
CC       protein are also present in many proteins constituting the protective
CC       envelope of other species.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   AlphaFoldDB; P81225; -.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR   InterPro; IPR000618; Insect_cuticle.
DR   Pfam; PF00379; Chitin_bind_4; 1.
DR   PRINTS; PR00947; CUTICLE.
DR   PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR   PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE   1: Evidence at protein level;
KW   Cuticle; Direct protein sequencing; Repeat.
FT   CHAIN           1..169
FT                   /note="Cuticle protein 21"
FT                   /id="PRO_0000196101"
FT   REPEAT          21..24
FT                   /note="1"
FT   REPEAT          27..30
FT                   /note="2"
FT   REPEAT          33..36
FT                   /note="3"
FT   REPEAT          39..42
FT                   /note="4"
FT   REPEAT          47..50
FT                   /note="5"
FT   REPEAT          53..56
FT                   /note="6"
FT   DOMAIN          65..135
FT                   /note="Chitin-binding type R&R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
FT   REPEAT          140..143
FT                   /note="7"
FT   REPEAT          146..149
FT                   /note="8"
FT   REPEAT          160..163
FT                   /note="9"
SQ   SEQUENCE   169 AA;  16879 MW;  529144B53A131BDE CRC64;
     GYLGAPAVYA PGAPIAARAY AAPVAYAAPA LRAAPVAYAA PAVAKVAAPV AYAAPAAVAA
     EYDPNPQYSY AYNVQDALTG DSKAQQETRD GDVVQGSYSL VEPDGSIRTV DYTADPVNGF
     NAVVHKEAGA HPAPVVAKVA APVAYAAPAI AKVAAPLAYA APAYGKASH