ID   CU22_BOMMO              Reviewed;         174 AA.
AC   O02388;
DT   15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Larval cuticle protein LCP-22;
DE   Flags: Precursor;
GN   Name=LCP22;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Kinshu X Showa; TISSUE=Epidermis;
RX   PubMed=9443370; DOI=10.1016/s0965-1748(97)00048-9;
RA   Nakato H., Takekoshi M., Togawa T., Izumi S., Tomino S.;
RT   "Purification and cDNA cloning of evolutionally conserved larval cuticle
RT   proteins of the silkworm, Bombyx mori.";
RL   Insect Biochem. Mol. Biol. 27:701-709(1997).
CC   -!- FUNCTION: Component of the cuticle of the larva of Bombyx mori.
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DR   EMBL; AB004767; BAA20475.1; -; mRNA.
DR   RefSeq; NP_001036828.1; NM_001043363.1.
DR   AlphaFoldDB; O02388; -.
DR   STRING; 7091.BGIBMGA000333-TA; -.
DR   EnsemblMetazoa; BGIBMGA000333-RA; BGIBMGA000333-TA; BGIBMGA000333.
DR   GeneID; 692363; -.
DR   KEGG; bmor:692363; -.
DR   CTD; 692363; -.
DR   eggNOG; ENOG502T7F2; Eukaryota.
DR   HOGENOM; CLU_065450_3_0_1; -.
DR   InParanoid; O02388; -.
DR   OrthoDB; 1459720at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR   InterPro; IPR000618; Insect_cuticle.
DR   Pfam; PF00379; Chitin_bind_4; 1.
DR   PRINTS; PR00947; CUTICLE.
DR   PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR   PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE   2: Evidence at transcript level;
KW   Cuticle; Reference proteome; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000255"
FT   CHAIN           17..174
FT                   /note="Larval cuticle protein LCP-22"
FT                   /id="PRO_0000006405"
FT   DOMAIN          82..153
FT                   /note="Chitin-binding type R&R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
SQ   SEQUENCE   174 AA;  18852 MW;  A54DBA63F17943F5 CRC64;
     MKFAVVFACM VAAVAAQVRY ENEFYKKNPY RYSTYRPFVS VTTPTPFLPI PISSVAPVRV
     VPKVSEGYGA ETVKFGNEIN PDGSYTYFYE TNNGIAAQEQ GVPRNLGGNP PAVPVVAQGS
     FSWTSPEGVP ISVNYVADEN GYQPTGNAIP TSPPVPEQIA RALAYIAKNI PLKK